{"id":"W4396503479","doi":"10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5485","title":"Assessing the Efficacy and Safety of Hydrocortisone, Ascorbic Acid, and Thiamine Combination Therapy for the Management of Sepsis and Septic Shock: A Systematic Review and Meta-Analysis of Randomized Controlled Trials","year":2024,"lang":"en","type":"review","venue":"","topic":"Vitamin C and Antioxidants Research","field":"Nursing","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Queen's University; University of British Columbia; University of Toronto","funders":"","keywords":"Ascorbic acid; Septic shock; Randomized controlled trial; Meta-analysis; Sepsis; Medicine; Thiamine; Intensive care medicine; Hydrocortisone; Shock (circulatory); Internal medicine; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008956741,0.002447792,0.01828089,0.003203547,0.0005619191,0.002460079,0.0019446,0.002225704,0.002346191],"category_scores_gemma":[0.01928698,0.001204369,0.02306452,0.003734345,0.0008872912,0.001421509,0.001388921,0.002163361,0.0001934344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001751674,"about_ca_system_score_gemma":0.002845812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005221931,"about_ca_topic_score_gemma":0.01222,"domain_scores_codex":[0.9954147,0.001923162,0.001498,0.0004906915,0.0005242956,0.0001490973],"domain_scores_gemma":[0.9895866,0.007753846,0.001689014,0.0002493176,0.0005619224,0.000159323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.01028493,0.000120361,0.002402572,0.4136409,0.5441114,0.00009322058,0.00009492103,0.0005306351,0.0005602898,0.0001057427,0.0004696855,0.02758525],"study_design_scores_gemma":[0.003193709,0.0007510426,0.003072636,0.01694244,0.9740788,0.00007813436,0.00005986011,0.0001845134,0.0001816938,0.0001551367,0.001271165,0.00003084993],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006260719,0.9927834,0.0002969381,0.00008926255,0.0001215959,0.0001969413,0.0001350261,0.00001112553,0.0001050381],"genre_scores_gemma":[0.1275863,0.8687552,0.001761356,0.0006878011,0.0001950898,0.000407844,0.0003717483,0.0000137875,0.0002208543],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01828089,"threshold_uncertainty_score":0.04736835,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1301139772132514,"score_gpt":0.4502530504470826,"score_spread":0.3201390732338312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}