{"id":"W4396503792","doi":"10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a3247","title":"The Role of M2-like Macrophages and Their Aggregation in the Formation of Honeycomb Cysts Expressing MUC5B in Idiopathic Pulmonary Fibrosis","year":2024,"lang":"en","type":"article","venue":"","topic":"Medical Imaging and Pathology Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Honeycomb; Idiopathic pulmonary fibrosis; Fibrosis; Macrophage; Pulmonary fibrosis; Pulmonary disease; Cell biology; Lung; Chemistry; Pathology; Medicine; Materials science; Biology; Internal medicine; Composite material; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008247182,0.0000700671,0.0001636032,0.0000812621,0.00004912557,0.00001169465,0.00005297158,0.00004377322,0.00000214494],"category_scores_gemma":[0.000129067,0.00003143458,0.00002815618,0.000178207,0.0001923262,0.00008083464,0.00003294309,0.0001643656,7.999157e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009200126,"about_ca_system_score_gemma":0.00001754391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007032873,"about_ca_topic_score_gemma":0.00002527832,"domain_scores_codex":[0.9992883,0.0001365388,0.0002609981,0.00009362871,0.0001192009,0.0001013826],"domain_scores_gemma":[0.9994487,0.0003422459,0.00004836963,0.0001220092,0.00002411192,0.00001460777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0001860195,0.0001563193,0.04409935,0.001398156,0.00003706455,0.00008472218,0.05021399,0.000006667343,0.1789131,0.0006522828,0.0003316654,0.7239206],"study_design_scores_gemma":[0.002420615,0.0007451631,0.3988717,0.01444861,0.0001919936,0.001029841,0.1110999,0.1200381,0.3279122,0.01837908,0.00445029,0.000412514],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9464525,0.04922062,0.0001826205,0.002173359,0.00006454971,0.0001766662,0.000002635816,0.00001567428,0.001711373],"genre_scores_gemma":[0.9984518,0.001251116,0.00009786186,0.0000991675,0.00002498208,0.00001768995,0.000003517211,0.000004451832,0.00004935619],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7235081,"threshold_uncertainty_score":0.1281865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01234963988911146,"score_gpt":0.262068268813174,"score_spread":0.2497186289240625,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}