{"id":"W4396508730","doi":"10.1007/s10914-024-09715-6","title":"Characterizing patterns of selection pressure on mammalian antiviral immune response","year":2024,"lang":"en","type":"article","venue":"Journal of Mammalian Evolution","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Immune system; Human genetics; Selection (genetic algorithm); Biology; Evolutionary biology; Computational biology; Genetics; Computer science; Gene; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004870837,0.0001317638,0.000243353,0.0005728031,0.0002156424,0.0005230732,0.0002435338,0.0002701869,0.001366588],"category_scores_gemma":[0.0007657103,0.0001318294,0.0001471357,0.0003696718,0.0003627545,0.0002590975,0.0003729039,0.0004994791,0.0001276771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002602368,"about_ca_system_score_gemma":0.000114948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002946788,"about_ca_topic_score_gemma":0.0008459702,"domain_scores_codex":[0.9997658,0.00008054607,0.00001279278,0.00005621156,0.00004373221,0.0000409208],"domain_scores_gemma":[0.9993941,0.0002827324,0.0001397453,0.00005997281,0.00005795693,0.00006563387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004237825,0.0000468844,0.1101402,0.00003021357,0.00009640462,0.00005898246,0.0001896818,0.0007075308,0.873662,0.0009277723,0.00008518987,0.0136314],"study_design_scores_gemma":[0.00001779622,0.0003101682,0.9545498,0.00001006124,0.00005720832,0.0003498097,0.0003569881,0.003672309,0.03904719,0.0006287073,0.0009852492,0.00001468788],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990471,0.00006225471,0.0002894074,0.00001434106,0.000001046137,0.000001605663,0.00003334168,0.000004121216,0.0005467483],"genre_scores_gemma":[0.9994512,0.00004053654,0.0002422128,0.00002741357,0.000003579206,0.000004520981,0.00006399586,0.000006469168,0.0001599713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001366588,"threshold_uncertainty_score":0.004571676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01015011219557249,"score_gpt":0.2494957769755504,"score_spread":0.2393456647799779,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}