{"id":"W4396517798","doi":"10.3389/fmicb.2024.1379400","title":"Isolation, characterization and therapeutic evaluation of a new Acinetobacter virus Abgy202141 lysing Acinetobacter baumannii","year":2024,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Department of Education of Guizhou Province; Guizhou Medical University; National Natural Science Foundation of China","keywords":"Acinetobacter baumannii; Acinetobacter; Microbiology; Biology; Virology; Galleria mellonella; ORFS; Antibiotic resistance; Virus; Phage therapy; Virulence; Bacteria; Antibiotics; Bacteriophage; Gene; Open reading frame; Pseudomonas aeruginosa; Genetics; Escherichia coli; Peptide sequence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001991243,0.000481086,0.0003698367,0.0003443543,0.000249653,0.0003452845,0.0002287783,0.000391285,0.0002733503],"category_scores_gemma":[0.0002640842,0.0001256668,0.0003498856,0.0003249934,0.0001954981,0.0002695915,0.0002706383,0.000360026,0.0001612383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002237389,"about_ca_system_score_gemma":0.0002721977,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002091942,"about_ca_topic_score_gemma":0.001685571,"domain_scores_codex":[0.9997901,0.00004070236,0.00002774522,0.0000468066,0.00006156373,0.00003293372],"domain_scores_gemma":[0.9998329,0.00003469227,0.00002532352,0.0000178548,0.00004581114,0.0000435173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002307712,0.00003201528,0.0005090993,0.0000271898,0.000003737349,0.00002915102,0.00001913268,0.00004274882,0.9983699,0.000009988111,0.000008959879,0.0009250751],"study_design_scores_gemma":[0.00002233835,0.001326798,0.0183247,0.00001585804,0.00005699239,0.0004677039,0.000140119,0.001577079,0.9758555,0.0000379383,0.002158645,0.00001628229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977474,0.0005251026,0.001140119,0.00003738841,0.00001266513,0.00007293175,0.0001743008,0.0000149497,0.0002751735],"genre_scores_gemma":[0.9849584,0.0009451284,0.01046533,0.00008670303,0.00001640123,0.0001365868,0.002202124,0.00002859217,0.001160668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002091942,"threshold_uncertainty_score":0.00415951,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01506340218636717,"score_gpt":0.2583667973406483,"score_spread":0.2433033951542811,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}