{"id":"W4396519032","doi":"10.1111/cas.16147","title":"In‐depth immune profiling of peripheral blood mononuclear cells in patients with pancreatic ductal adenocarcinoma reveals discriminative immune subpopulations","year":2024,"lang":"en","type":"article","venue":"Cancer Science","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Cancer Center Amsterdam; Associazione Italiana per la Ricerca sul Cancro; European Research Council; Nederlandse Organisatie voor Wetenschappelijk Onderzoek","keywords":"Immune system; Peripheral blood mononuclear cell; Medicine; Pancreatic ductal adenocarcinoma; Pancreas; Mass cytometry; CD86; Pancreatic cancer; Immunology; Oncology; Internal medicine; Cancer; Biology; T cell; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001622906,0.0001723446,0.0002305693,0.000365358,0.0002008622,0.000391318,0.00008231485,0.0002613131,0.001350053],"category_scores_gemma":[0.0003492727,0.00008936391,0.0001220097,0.0002721603,0.00008606629,0.0001671389,0.000183912,0.0002279483,0.0002636819],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009825294,"about_ca_system_score_gemma":0.00006522299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002625293,"about_ca_topic_score_gemma":0.000326921,"domain_scores_codex":[0.9998512,0.00003791664,0.00001608725,0.00004476628,0.00002041914,0.00002960011],"domain_scores_gemma":[0.9998542,0.00003428398,0.00003630059,0.00001017393,0.00002326614,0.00004168683],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001355811,0.0001079706,0.9177766,0.00007331974,0.00004528222,0.0006515775,0.0001972071,0.00009239757,0.06507239,0.00004297739,0.0003660698,0.01421823],"study_design_scores_gemma":[0.00001860285,0.000568512,0.9852374,0.00001752829,0.00005446084,0.00304179,0.0005099041,0.0005810846,0.008226302,0.00009748804,0.001639993,0.000007057311],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983912,0.0005410591,0.0003402371,0.00003112038,0.000007820257,0.000010652,0.000208048,0.000008782059,0.0004609498],"genre_scores_gemma":[0.9989477,0.0001498936,0.0002789779,0.00005272801,0.00001295341,0.00001391081,0.0002046004,0.00000204484,0.0003372432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001350053,"threshold_uncertainty_score":0.004516363,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02172171256062119,"score_gpt":0.3269092701480714,"score_spread":0.3051875575874502,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}