{"id":"W4396538978","doi":"10.1016/j.cbd.2024.101238","title":"Transcriptomic profiling of Rana [Lithobates] catesbeiana back skin during natural and thyroid hormone-induced metamorphosis under different temperature regimes with particular emphasis on innate immune system components","year":2024,"lang":"en","type":"article","venue":"Comparative Biochemistry and Physiology Part D Genomics and Proteomics","topic":"Amphibian and Reptile Biology","field":"Environmental Science","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency; University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Alliance de recherche numérique du Canada; Genome British Columbia; Genome Canada","keywords":"Metamorphosis; Biology; Transcriptome; Innate immune system; Tadpole (physics); Lithobates; Immune system; Thyroid; Gene expression; Amphibian; Internal medicine; Cell biology; Gene; Endocrinology; Immunology; Ecology; Larva; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009542922,0.0003260889,0.0005213533,0.00002725525,0.0001921715,0.00003837797,0.000106199,0.0001759535,0.000009173777],"category_scores_gemma":[0.000001766184,0.0002239221,0.00006344126,0.00008513321,0.000536859,0.00005214081,0.00009556265,0.0002658555,0.000003810376],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006379922,"about_ca_system_score_gemma":0.00001496149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002241711,"about_ca_topic_score_gemma":0.000004165872,"domain_scores_codex":[0.9986816,0.0001011839,0.0002945378,0.0005926138,0.00006896364,0.0002611081],"domain_scores_gemma":[0.9995299,0.0000431374,0.0001149916,0.0001949875,0.00001360101,0.0001033638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006247811,0.00004004251,0.0006599141,0.0002326052,0.0002131573,0.000003846493,0.0005126998,0.00007943221,0.9975063,0.00007843045,0.00001073603,0.00003805272],"study_design_scores_gemma":[0.0007547857,0.0002260585,0.02828028,0.00011008,0.00007072715,0.00006441223,0.0004280602,0.001833408,0.9678722,0.00004125206,0.00002897771,0.0002897257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937589,0.005489674,0.000007711303,0.00008689842,0.00007393986,0.0004732208,0.0000540939,0.00001972438,0.00003583072],"genre_scores_gemma":[0.999153,0.000378927,0.0002161709,0.00002204822,0.00004494295,0.00003670931,0.0000684092,0.00001562977,0.00006421468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02963407,"threshold_uncertainty_score":0.9131278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0139775743591412,"score_gpt":0.2201196305531944,"score_spread":0.2061420561940532,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}