{"id":"W4396580435","doi":"10.3390/cells13090780","title":"Actin Cytoskeleton Remodeling Accompanied by Redistribution of Adhesion Proteins Drives Migration of Cells in Different EMT States","year":2024,"lang":"en","type":"article","venue":"Cells","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Russian Science Foundation","keywords":"Adherens junction; Cell biology; Vinculin; Catenin; Epithelial–mesenchymal transition; Cell migration; Cadherin; Cell adhesion; Chemistry; Actin cytoskeleton; Actin; Focal adhesion; Cytoskeleton; Cell; Biology; Signal transduction; Wnt signaling pathway; Downregulation and upregulation; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000997598,0.0001132991,0.0001435103,0.00006092522,0.00002014383,0.00001612134,0.00008238287,0.0001047588,0.0000210131],"category_scores_gemma":[0.00001191699,0.0001008022,0.0000889287,0.00008746498,0.00001755655,0.00000765658,0.00004422486,0.00009250983,0.000002728415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002742711,"about_ca_system_score_gemma":0.00003067831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009885084,"about_ca_topic_score_gemma":0.00004459223,"domain_scores_codex":[0.9991997,0.00004307102,0.000303588,0.0002313909,0.00009963425,0.0001225629],"domain_scores_gemma":[0.9996303,0.000015379,0.00009548046,0.0001721504,0.00005637608,0.00003035886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004143635,0.0001072504,0.00001083291,0.00009399388,0.00001405481,4.707845e-7,0.0001019821,0.0001250354,0.996532,0.000041785,0.0021488,0.0007823066],"study_design_scores_gemma":[0.0001406103,0.0001868661,0.0000236973,0.0001163843,0.00001315892,6.112743e-7,0.0001414506,0.01449756,0.9776452,0.0001167378,0.007026015,0.00009173151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983547,0.0005482154,0.01517609,0.00007260319,0.0002157358,0.0002242631,0.0001300271,0.000008065588,0.00007794226],"genre_scores_gemma":[0.9982612,0.0005561802,0.0001643198,0.000007010323,0.00005374722,0.00001110174,0.0006945201,0.00001378847,0.0002381564],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01888687,"threshold_uncertainty_score":0.4110593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006907518482635598,"score_gpt":0.2382121261373041,"score_spread":0.2313046076546685,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}