{"id":"W4396586809","doi":"10.1158/1538-7445.sabcs23-po4-13-01","title":"Abstract PO4-13-01: A randomised trial comparing 6-monthly dosing of adjuvant zoledronate with a single one-time dose in patients with early breast cancer (REaCT-ZOL): Quality of life and toxicity outcomes","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Bone health and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hamilton Health Sciences; Juravinski Cancer Centre; McMaster University; Markham Stouffville Hospital; Ottawa Hospital","funders":"","keywords":"Medicine; Dosing; Breast cancer; Adjuvant; Internal medicine; Oncology; Quality of life (healthcare); Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003082651,0.001502248,0.003901818,0.0006533854,0.0004558933,0.001197191,0.001332833,0.002199406,0.01009219],"category_scores_gemma":[0.003251762,0.0007939836,0.002981213,0.0006185636,0.001646957,0.0012484,0.0007652901,0.003439552,0.0013998],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009143897,"about_ca_system_score_gemma":0.001711178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000949892,"about_ca_topic_score_gemma":0.00142912,"domain_scores_codex":[0.9983485,0.00100899,0.0001390043,0.0002372675,0.0001040427,0.0001622316],"domain_scores_gemma":[0.9975268,0.0008127584,0.0006437529,0.0002059829,0.0001377547,0.0006729848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9896795,0.003080823,0.0002749859,0.0002954476,0.0004003655,0.00001471291,0.00001861254,0.0001483272,0.0009056427,0.00003580841,0.0001207048,0.005025065],"study_design_scores_gemma":[0.9425616,0.05623871,0.0005756227,0.00001414834,0.0002147193,0.00001246452,0.000006308267,0.0001151752,0.0001096701,0.00003528469,0.0001110363,0.000005314313],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887349,0.003134692,0.0004980837,0.0005916469,0.0005595077,0.004469923,0.0008491221,0.00008457644,0.001077567],"genre_scores_gemma":[0.9827539,0.002158766,0.001957947,0.0008759919,0.0006571901,0.007179387,0.001321026,0.00002314926,0.003072532],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01009219,"threshold_uncertainty_score":0.03376174,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09602372343925715,"score_gpt":0.4043524949041157,"score_spread":0.3083287714648586,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}