{"id":"W4396587839","doi":"10.1158/1538-7445.sabcs23-po3-15-04","title":"Abstract PO3-15-04: Oncotype DX Recurrence Score as an Informative Tool to Optimize Neoadjuvant Therapy in HR-positive, HER2-negative Breast Cancers","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency; Spinal Cord Injury BC","funders":"","keywords":"Medicine; Oncology; Internal medicine; Breast cancer; HER2 negative; Gynecology; Cancer; Metastatic breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001053446,0.0002998075,0.0003902421,0.0005751204,0.0001581158,0.0004901782,0.0002636357,0.000215722,0.001709009],"category_scores_gemma":[0.002254956,0.00009823589,0.0004600416,0.0005674238,0.0001361036,0.0002065321,0.0002980036,0.0003041557,0.0004192798],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003112419,"about_ca_system_score_gemma":0.0002830844,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008214266,"about_ca_topic_score_gemma":0.001933673,"domain_scores_codex":[0.9995925,0.0001546664,0.00006071744,0.00004240313,0.0001139182,0.00003577567],"domain_scores_gemma":[0.9985404,0.0003845253,0.0005889093,0.00004689222,0.0001888389,0.0002505795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003516625,0.0001440706,0.9739342,0.00004706673,0.0001065668,0.00007810726,0.00002500878,0.0004083847,0.001326189,0.00002536432,0.0007925428,0.01959596],"study_design_scores_gemma":[0.0001178964,0.001656965,0.9932758,0.00001269558,0.0001553443,0.0003986225,0.00006044415,0.002269232,0.001089875,0.00004532609,0.0009066715,0.00001128355],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971647,0.000371035,0.0004483117,0.0001049662,0.00001811851,0.00005695837,0.000553887,0.00001822477,0.001263859],"genre_scores_gemma":[0.9978856,0.00009664405,0.0008208057,0.00002744015,0.00001735412,0.00004656989,0.0006399212,0.000005300566,0.0004603925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001709009,"threshold_uncertainty_score":0.005717218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04410454100374414,"score_gpt":0.3968007927289976,"score_spread":0.3526962517252534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}