{"id":"W4396590741","doi":"10.1158/1538-7445.sabcs23-gs01-12","title":"Abstract GS01-12: MONARCH 3: Final overall survival results of abemaciclib plus a nonsteroidal aromatase inhibitor as first-line therapy for HR+, HER2- advanced breast cancer","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Advanced Breast Cancer Therapies","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Regional Municipality of Durham","funders":"","keywords":"Aromatase inhibitor; Aromatase; Medicine; Nonsteroidal; Breast cancer; Internal medicine; Oncology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001879183,0.001047137,0.001668113,0.0005102866,0.0004520644,0.001107129,0.0007758781,0.0008896226,0.007250329],"category_scores_gemma":[0.0009236086,0.0003023772,0.002584336,0.0004625806,0.0008495265,0.0006835903,0.0005438288,0.00275669,0.001030012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002012257,"about_ca_system_score_gemma":0.002786478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003932944,"about_ca_topic_score_gemma":0.01792449,"domain_scores_codex":[0.9994863,0.0002222491,0.00003214322,0.00006503613,0.00008545553,0.0001087222],"domain_scores_gemma":[0.9992638,0.00008066263,0.0001550176,0.0001148011,0.00007438826,0.0003113851],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.8080446,0.01955076,0.005130664,0.001728431,0.004497603,0.0001635882,0.0001430489,0.003384285,0.03308934,0.0005246862,0.01897688,0.1047662],"study_design_scores_gemma":[0.3831086,0.5142483,0.05549569,0.0002358829,0.005973348,0.0005663465,0.0001614475,0.002413354,0.01532945,0.0007704588,0.02156126,0.0001358103],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9667564,0.008680666,0.0009333214,0.001387362,0.0003963643,0.0015572,0.01168775,0.0004984707,0.008102475],"genre_scores_gemma":[0.9681607,0.002527354,0.001231692,0.002191417,0.0002693611,0.0009285088,0.01465442,0.0001027433,0.009933824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007250329,"threshold_uncertainty_score":0.0242548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1009803284823002,"score_gpt":0.4373257798171252,"score_spread":0.336345451334825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}