{"id":"W4396590827","doi":"10.1158/1538-7445.sabcs23-po2-04-10","title":"Abstract PO2-04-10: Effect of Alpelisib Dose Modification for AE Management on Progression-Free Survival and Treatment Duration in SOLAR-1 and BYLieve Clinical Trials","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Peptidase Inhibition and Analysis","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Medicine; Clinical trial; Duration (music); Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006617042,0.000101179,0.0004040154,0.0003256074,0.00005096927,0.00005119965,0.00004341945,0.0000847421,0.0001103487],"category_scores_gemma":[0.0007428554,0.00006568356,0.0001112703,0.000238031,0.0000993683,0.00005710602,0.00003085172,0.0001583391,0.000006825073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001587798,"about_ca_system_score_gemma":0.0000879496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009052666,"about_ca_topic_score_gemma":0.00007861762,"domain_scores_codex":[0.9980878,0.0004659892,0.0005153096,0.0003510088,0.000405598,0.0001742696],"domain_scores_gemma":[0.9979741,0.001534527,0.00006558046,0.000226961,0.00009103898,0.0001078025],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.008392123,0.0005517669,0.003609741,0.001947038,0.0004506412,0.00007537451,0.0002257371,0.00001105342,0.02528872,0.0008428684,0.005600348,0.9530046],"study_design_scores_gemma":[0.08720753,0.02552951,0.5236622,0.02662301,0.00171873,0.00001406073,0.001598816,0.02489368,0.2752959,0.003001145,0.0294389,0.00101649],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922123,0.001008082,0.00003951935,0.003671279,0.0000446743,0.001923413,0.00007971255,0.00001855675,0.001002451],"genre_scores_gemma":[0.9960383,0.00188864,0.00008196485,0.00001428874,0.0001815721,0.00066331,0.00008650319,0.0000131568,0.001032223],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9519881,"threshold_uncertainty_score":0.2678498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3073220384706638,"score_gpt":0.5850373850860928,"score_spread":0.277715346615429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}