{"id":"W4396592360","doi":"10.1007/s13555-024-01157-5","title":"Upadacitinib Rapidly Improves Patient-Reported Outcomes in Atopic Dermatitis: 16-Week Results from Phase 3 Clinical Trials (Measure Up 1 and 2)","year":2024,"lang":"en","type":"article","venue":"Dermatology and Therapy","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; SKiN Health; University of Calgary","funders":"","keywords":"Atopic dermatitis; Medicine; Quality of life (healthcare); Clinical trial; Dermatology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004149389,0.0007476528,0.002155496,0.00036633,0.0002868385,0.0008202122,0.0004501849,0.0006899931,0.001519049],"category_scores_gemma":[0.002125236,0.0002700738,0.002686868,0.0005134771,0.0003385888,0.0005216805,0.0003915478,0.001600897,0.0002255825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004822008,"about_ca_system_score_gemma":0.0007789384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004687117,"about_ca_topic_score_gemma":0.001543538,"domain_scores_codex":[0.9986399,0.0007372167,0.0001162273,0.0001370457,0.0002064857,0.0001631909],"domain_scores_gemma":[0.9988311,0.000287146,0.0004747361,0.000110515,0.0001185218,0.0001780371],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6282922,0.02113928,0.01878143,0.003564111,0.01091653,0.0002293551,0.000348582,0.002536303,0.03362177,0.0001636512,0.005252176,0.2751547],"study_design_scores_gemma":[0.4339564,0.3955417,0.1447112,0.0003585135,0.008185474,0.0006013876,0.0001379284,0.001661692,0.007921271,0.0002142131,0.006614324,0.00009599136],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9801911,0.01537283,0.0004734624,0.0002636746,0.0001022653,0.00118485,0.001364218,0.00005837618,0.0009892491],"genre_scores_gemma":[0.9876338,0.006217591,0.001032466,0.0005695398,0.0001197523,0.001510659,0.002029586,0.00001844417,0.0008681811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004149389,"threshold_uncertainty_score":0.02194434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0809078995283674,"score_gpt":0.3963929099982119,"score_spread":0.3154850104698445,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}