{"id":"W4396613915","doi":"10.51731/cjht.2024.884","title":"Anticytokine Therapy and Corticosteroids for Cytokine Release Syndrome and for Neurotoxicity Following T-Cell Engager or CAR T-Cell Therapy","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cytokine release syndrome; Medicine; Anakinra; Internal medicine; Oncology; Chimeric antigen receptor; T cell; Immunology; Immune system","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001283518,0.0002608093,0.0007185916,0.0008496209,0.000336446,0.0001330535,0.0002038699,0.0002103973,0.00003512633],"category_scores_gemma":[0.0004354931,0.0001876294,0.0001899398,0.0003674427,0.0002325479,0.0001423802,0.00002160451,0.0006032559,6.537602e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002519262,"about_ca_system_score_gemma":0.002224467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000476832,"about_ca_topic_score_gemma":0.0002294282,"domain_scores_codex":[0.9980006,0.00008391208,0.0006287268,0.0003447525,0.0002196442,0.0007224071],"domain_scores_gemma":[0.9984993,0.0005697972,0.0001695012,0.0003009735,0.0001612967,0.0002991086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00162755,0.0001100281,0.003163271,0.001827892,0.0002704979,0.00229994,0.0007531628,0.000002323133,0.1596307,0.00006986661,0.002730633,0.8275141],"study_design_scores_gemma":[0.02063153,0.0347967,0.007188248,0.001796729,0.0001657084,0.007297493,0.003518905,0.0009111679,0.1281872,0.001841897,0.7928316,0.0008328463],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8777307,0.1051121,0.000452159,0.01403846,0.000297748,0.002166072,0.00007363846,0.0001061286,0.00002300663],"genre_scores_gemma":[0.9848395,0.01241204,0.00113785,0.0007226895,0.00003954327,0.00008415658,0.000005183235,0.00007871161,0.0006802995],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8266813,"threshold_uncertainty_score":0.7651305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07920129161709988,"score_gpt":0.3448582712694659,"score_spread":0.265656979652366,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}