{"id":"W4396622567","doi":"10.1155/2024/5575030","title":"The Right Formula for Acne: Importance of Vehicle Formulation in Tazarotene 0.045% Lotion Design, Application, Tolerability, and Efficacy","year":2024,"lang":"en","type":"article","venue":"Dermatologic Therapy","topic":"Acne and Rosacea Treatments and Effects","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bausch Health; Ortho Dermatologics","keywords":"Lotion; Tazarotene; Tolerability; Medicine; Acne; Dermatology; Pharmacology; Adverse effect","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001290596,0.0004859023,0.0006251161,0.0006826086,0.0002641175,0.001278843,0.0003773583,0.001117128,0.002438172],"category_scores_gemma":[0.001633877,0.000349093,0.0004385177,0.0002413227,0.0004935069,0.001671078,0.0003808939,0.00142836,0.00140121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003545714,"about_ca_system_score_gemma":0.0004489566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00078118,"about_ca_topic_score_gemma":0.001002009,"domain_scores_codex":[0.9993988,0.0001461132,0.00008223808,0.00006774985,0.0002647944,0.00004029826],"domain_scores_gemma":[0.9995364,0.0001485303,0.0001158534,0.00003472331,0.0001126484,0.00005194603],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001359814,0.0006562265,0.001191427,0.001502091,0.00006243189,0.0006632344,0.0001949389,0.0007003716,0.5650972,0.005595147,0.00732296,0.4156541],"study_design_scores_gemma":[0.001665273,0.01196986,0.01293257,0.001509738,0.0004299482,0.009623356,0.0004144025,0.008249793,0.55739,0.004304703,0.3912694,0.000240821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4592253,0.2874793,0.1683348,0.03276609,0.006405122,0.00311502,0.001152418,0.002463378,0.03905863],"genre_scores_gemma":[0.7206191,0.103104,0.1497368,0.005703567,0.001900313,0.001200574,0.0007455406,0.000669388,0.01632066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002438172,"threshold_uncertainty_score":0.008156478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02109012430818374,"score_gpt":0.3078175684560207,"score_spread":0.2867274441478369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}