{"id":"W4396623620","doi":"10.1016/j.xhgg.2024.100303","title":"A functional schizophrenia-associated genetic variant near the TSNARE1 and ADGRB1 genes","year":2024,"lang":"en","type":"article","venue":"Human Genetics and Genomics Advances","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute of General Medical Sciences; National Human Genome Research Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Schizophrenia (object-oriented programming); Gene; Genetics; Biology; Computational biology; Psychology; Psychiatry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001903563,0.0005707247,0.0003394726,0.0006327372,0.0002594893,0.000225249,0.000196782,0.0004327645,0.002223829],"category_scores_gemma":[0.0005102108,0.0001598058,0.0004060454,0.0003773533,0.0002716791,0.00006676433,0.0003462059,0.0004183121,0.0002480257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002954849,"about_ca_system_score_gemma":0.0002714016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002264365,"about_ca_topic_score_gemma":0.003488672,"domain_scores_codex":[0.9997163,0.00003423263,0.00003066315,0.00009959439,0.00009181788,0.00002745436],"domain_scores_gemma":[0.9997883,0.00005477843,0.00008423204,0.0000188817,0.00001249209,0.00004125767],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00070746,0.00004193797,0.02546862,0.00006463181,0.0001034297,0.002429928,0.000135323,0.0005435478,0.9641666,0.000489417,0.00008817313,0.005760959],"study_design_scores_gemma":[0.0002290248,0.0007348609,0.7703084,0.00007720608,0.0003880397,0.01863113,0.0003071228,0.005999116,0.1970191,0.00124285,0.00497993,0.00008317199],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972479,0.0002557352,0.00138969,0.00006391826,0.000008639547,0.000009459907,0.0005411238,0.00003121134,0.0004522208],"genre_scores_gemma":[0.9971343,0.0001028028,0.001793926,0.00003955047,0.000004843179,0.00001193588,0.000431819,0.00001057775,0.0004701272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002264365,"threshold_uncertainty_score":0.007439435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0128970821477641,"score_gpt":0.250327207005063,"score_spread":0.2374301248572989,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}