{"id":"W4396640641","doi":"10.1016/j.ocarto.2024.100479","title":"Transcriptomics and metabolomics: Challenges of studying obesity in osteoarthritis","year":2024,"lang":"en","type":"article","venue":"Osteoarthritis and Cartilage Open","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Arthritis Society; University Health Network","funders":"Canada Research Chairs","keywords":"Metabolomics; Osteoarthritis; Transcriptome; Obesity; Omics; Bioinformatics; Medicine; Biology; Internal medicine; Pathology; Gene expression; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01372672,0.0008155043,0.003507476,0.00423422,0.0006212404,0.004512559,0.001241748,0.002007965,0.00213166],"category_scores_gemma":[0.01361602,0.0003923992,0.001952364,0.00686737,0.001654888,0.004778251,0.001876203,0.002832823,0.0006621978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001317457,"about_ca_system_score_gemma":0.00441974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002459224,"about_ca_topic_score_gemma":0.003853337,"domain_scores_codex":[0.9932802,0.003400583,0.001082084,0.000771617,0.001281447,0.0001840018],"domain_scores_gemma":[0.9728219,0.0215444,0.002132313,0.0008728218,0.002248701,0.0003799605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007133412,0.0001439571,0.02089509,0.1597711,0.00411305,0.001678913,0.002189324,0.003654181,0.0301889,0.03923701,0.03125426,0.7061608],"study_design_scores_gemma":[0.0001444384,0.0007435046,0.0712597,0.06627402,0.003234863,0.003689552,0.00676049,0.006719882,0.00897132,0.1761063,0.6556796,0.0004162642],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006924727,0.9477871,0.01768788,0.0217421,0.001394925,0.0001221228,0.001903837,0.00008841223,0.002348862],"genre_scores_gemma":[0.05438391,0.8906445,0.03908586,0.009327787,0.003170053,0.0004758239,0.001803569,0.00006055124,0.001047926],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01372672,"threshold_uncertainty_score":0.07259476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02567750357791769,"score_gpt":0.2676840182109316,"score_spread":0.2420065146330139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}