{"id":"W4396665246","doi":"10.1139/apnm-2024-0016","title":"Better maintenance of enzymatic capacity and higher levels of substrate transporter proteins in skeletal muscle of aging female mice","year":2024,"lang":"en","type":"article","venue":"Applied Physiology Nutrition and Metabolism","topic":"Muscle metabolism and nutrition","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science","keywords":"Internal medicine; Endocrinology; Plantaris muscle; Skeletal muscle; Citrate synthase; Creatine kinase; Glycolysis; Biology; Phosphofructokinase; Lactate dehydrogenase; Pyruvate kinase; Hexokinase; Gastrocnemius muscle; Soleus muscle; Enzyme; Metabolism; Biochemistry; Medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002428378,0.0005167489,0.000389858,0.0008033162,0.0001542979,0.0002925801,0.0001848921,0.000288528,0.001917592],"category_scores_gemma":[0.0001349911,0.0002168358,0.0003818577,0.0001983449,0.0001950139,0.0004384711,0.0002126818,0.0004239979,0.0004040211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001335626,"about_ca_system_score_gemma":0.0001160428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000373042,"about_ca_topic_score_gemma":0.0005166536,"domain_scores_codex":[0.9998391,0.00001533823,0.00001688991,0.00007257885,0.00002756549,0.00002849497],"domain_scores_gemma":[0.9997652,0.000009031913,0.0001198526,0.00001721573,0.00002707578,0.0000615625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004034462,0.00005153108,0.003311971,0.00003427371,0.00001593359,0.00007691542,0.00003594657,0.00001575998,0.9932896,0.00005334563,0.00003687483,0.002674342],"study_design_scores_gemma":[0.00009286045,0.003381417,0.3449016,0.00003743038,0.0002433893,0.001720697,0.000374792,0.0005830316,0.6419498,0.0002668283,0.006408518,0.00003971894],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946123,0.00156448,0.002216221,0.00008034445,0.00004385968,0.00001040775,0.0008769167,0.00006558817,0.0005299089],"genre_scores_gemma":[0.9854715,0.0021235,0.002895235,0.0001676941,0.00005849492,0.00007968999,0.001572091,0.00009555588,0.007536175],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001917592,"threshold_uncertainty_score":0.006415009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01379354790767138,"score_gpt":0.2284046103284065,"score_spread":0.2146110624207351,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}