{"id":"W4396666490","doi":"10.3390/biomedicines12051021","title":"Naturally Occurring Norsteroids and Their Design and Pharmaceutical Application","year":2024,"lang":"en","type":"article","venue":"Biomedicines","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lethbridge College","funders":"","keywords":"Natural product; Biology; Computational biology; Biological organism; Ecology; Biochemical engineering; Biological materials; Engineering; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001417833,0.00009480628,0.00006894908,0.00004125963,0.0000340528,0.00002308019,0.00004710065,0.00006086947,0.000003220973],"category_scores_gemma":[0.00002184967,0.0000608371,0.00001302383,0.00007568447,0.00008842886,0.000003625204,0.00007551201,0.00006361091,0.000001539732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002692154,"about_ca_system_score_gemma":0.00001097212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005748258,"about_ca_topic_score_gemma":0.000001272793,"domain_scores_codex":[0.9995015,0.00001654894,0.00007679823,0.0002616864,0.00004087577,0.0001026099],"domain_scores_gemma":[0.9998028,0.00001709312,0.00001041378,0.00009129364,0.00002124259,0.0000571462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002977281,0.000005164124,0.0004193101,0.0001041241,0.00002582166,0.00000182163,0.00003949196,3.521536e-7,0.8214271,0.00008625809,0.00167135,0.1761895],"study_design_scores_gemma":[0.0005409048,0.0003809911,0.004288437,0.00007990727,0.00004431861,0.0002194211,0.00007263554,0.007727882,0.2263181,0.0003154348,0.7597075,0.0003044788],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9323655,0.05778658,0.00683749,0.002215623,0.0003489261,0.0002706069,0.00000532142,0.00004213838,0.0001277948],"genre_scores_gemma":[0.9972361,0.001182485,0.0004871713,0.0003231052,0.0005188952,0.000008124858,0.00002645332,0.000009184841,0.0002085321],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7580362,"threshold_uncertainty_score":0.2480865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01173350573724454,"score_gpt":0.2830505795945843,"score_spread":0.2713170738573398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}