{"id":"W4396691671","doi":"10.2196/56884","title":"The Roles of NOTCH3 p.R544C and Thrombophilia Genes in Vietnamese Patients With Ischemic Stroke: Study Involving a Hierarchical Cluster Analysis","year":2024,"lang":"en","type":"article","venue":"JMIR Bioinformatics and Biotechnology","topic":"Cerebrovascular and genetic disorders","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bộ Giáo dục và Ðào tạo","keywords":"CADASIL; Medicine; Thrombophilia; Methylenetetrahydrofolate reductase; Stroke (engine); Internal medicine; Modified Rankin Scale; Glasgow Coma Scale; Leukoencephalopathy; Creatinine; Cardiology; Gastroenterology; Ischemic stroke; Disease; Thrombosis; Gene; Surgery; Genetics; Ischemia; Allele; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009789501,0.0002784273,0.0003169571,0.001061513,0.000552992,0.0004544032,0.0002511466,0.0001444917,0.001243869],"category_scores_gemma":[0.002469276,0.0001474218,0.000537585,0.0008895895,0.0002925427,0.000143476,0.0004174994,0.0002164761,0.0001407938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005861064,"about_ca_system_score_gemma":0.0008275289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01915709,"about_ca_topic_score_gemma":0.01328974,"domain_scores_codex":[0.9993698,0.0002760743,0.00004953819,0.0001285193,0.00006271592,0.0001133682],"domain_scores_gemma":[0.9986947,0.0004141509,0.0002814459,0.0001180799,0.0002489901,0.0002426882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002064862,0.00003646829,0.9941268,0.00001280083,0.0001037149,0.0001617525,0.0005288649,0.0003123906,0.000567999,0.00005876231,0.0001483733,0.003735555],"study_design_scores_gemma":[0.00002181006,0.0001493411,0.9888815,0.00001091558,0.00009814675,0.0004757112,0.001634259,0.007948878,0.0002823966,0.0001657335,0.0003202549,0.00001106189],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994247,0.00003361338,0.0003371535,0.00002225832,0.000002160289,0.00001097426,0.00007007428,0.000002461954,0.0000966118],"genre_scores_gemma":[0.999455,0.00001511497,0.0003122997,0.000004459804,0.000002154912,0.000009447404,0.000135282,0.000001550916,0.0000645879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01915709,"threshold_uncertainty_score":0.03809112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003926845986968771,"score_gpt":0.2338338600837031,"score_spread":0.2299070140967343,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}