{"id":"W4396696664","doi":"10.14740/wjon1860","title":"Genetic Evidence for a Causal Relationship Between Innate Leukocytes and the Risk of Digestive System Cancers in East Asians and Europeans","year":2024,"lang":"en","type":"article","venue":"World Journal of Oncology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Heilongjiang Provincial Postdoctoral Science Foundation; China Postdoctoral Science Foundation; National Natural Science Foundation of China; Harbin Medical University","keywords":"Medicine; Odds ratio; Internal medicine; Cancer; Confidence interval; Mendelian randomization; Population; Oncology; Demography; Genotype; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002522801,0.000560041,0.0005258206,0.001027032,0.0003699078,0.0008445563,0.0003994396,0.0006914314,0.004569819],"category_scores_gemma":[0.005239197,0.0003259547,0.001532058,0.001475623,0.0005617568,0.0003607515,0.0005336636,0.0004724219,0.0002267645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001701358,"about_ca_system_score_gemma":0.0002475265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002924843,"about_ca_topic_score_gemma":0.002237536,"domain_scores_codex":[0.9988411,0.0004526934,0.0001670999,0.0003469286,0.00009722725,0.0000949536],"domain_scores_gemma":[0.996564,0.001559756,0.001050185,0.0003909471,0.000222052,0.0002131429],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001236312,0.00003614786,0.9863923,0.0001669469,0.002819754,0.0004820787,0.0002487718,0.0001625296,0.002258445,0.0003450614,0.000185045,0.005666503],"study_design_scores_gemma":[0.00006253549,0.0001609807,0.9945512,0.00008235114,0.002224652,0.0007321012,0.0002445083,0.0004007215,0.0003440876,0.0005550703,0.0006276738,0.00001407161],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932814,0.004118336,0.000859058,0.000239215,0.0000303114,0.00000912833,0.0004853069,0.00001265011,0.0009645756],"genre_scores_gemma":[0.9981516,0.0008604336,0.0004676299,0.00009995736,0.00002797547,0.000007707656,0.0002194264,0.000005795942,0.0001594138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004569819,"threshold_uncertainty_score":0.01528758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05446429892092015,"score_gpt":0.3068517753038661,"score_spread":0.252387476382946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}