{"id":"W4396709309","doi":"10.1101/2024.05.04.24306873","title":"Elevated polyreactive immunoglobulin G in immune mediated liver injuries with the need for immunosuppressive therapy","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Immune system; Antibody; Immunology; Immunoglobulin G; Immunoglobulin M; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005871251,0.000246328,0.0003004347,0.0006956778,0.0002528638,0.0003907623,0.000206006,0.0003084254,0.001671053],"category_scores_gemma":[0.001916472,0.0001010736,0.0001821485,0.0005320647,0.0003113286,0.0002651547,0.0002739762,0.0003037413,0.0002362254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002432535,"about_ca_system_score_gemma":0.0001564053,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002831044,"about_ca_topic_score_gemma":0.0002055312,"domain_scores_codex":[0.9995608,0.0001392337,0.00006658191,0.00007628603,0.00008795823,0.00006911311],"domain_scores_gemma":[0.9980938,0.0004418165,0.001062188,0.00008103276,0.0001175369,0.000203673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002821086,0.00003224454,0.9957514,0.00001569675,0.00001553399,0.0005944249,0.00002498063,0.00001672255,0.0007103488,0.00001603728,0.00004174191,0.002498702],"study_design_scores_gemma":[0.00001177904,0.0002933277,0.9923307,0.00001500919,0.00003171627,0.006107201,0.0001146498,0.0001812589,0.0005957516,0.00004122825,0.0002750258,0.000002358636],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987022,0.0005963155,0.0001037554,0.00002981685,0.000006470159,0.0000079295,0.00003852403,0.000003521514,0.0005115194],"genre_scores_gemma":[0.9997749,0.00005853923,0.00005212628,0.00002655761,0.00001298977,0.000002878361,0.00003236187,5.868762e-7,0.00003904558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001671053,"threshold_uncertainty_score":0.0055902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01759172167753776,"score_gpt":0.2713060479560701,"score_spread":0.2537143262785324,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}