{"id":"W4396738160","doi":"10.1016/j.fbio.2024.104276","title":"Enzymatic characterization and synergistic effects of protease combinations on DPP-IV inhibitory peptide release from bovine casein","year":2024,"lang":"en","type":"article","venue":"Food Bioscience","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Science Fund for Distinguished Young Scholars of Guangxi Province; National Natural Science Foundation of China","keywords":"Papain; Proteases; Chemistry; Casein; Peptide; Protease; Hydrolysate; Enzyme; Hydrolysis; Biochemistry; Enzymatic hydrolysis; IC50; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001182083,0.0001324961,0.0001214027,0.00008286146,0.00008433186,0.00005066408,0.0001134689,0.0000702819,0.0000045546],"category_scores_gemma":[0.0003286411,0.0001093038,0.00004799443,0.0001966985,0.000193099,0.0000140626,0.00007717327,0.00006916773,0.000005809496],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001474712,"about_ca_system_score_gemma":0.00006763126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003413792,"about_ca_topic_score_gemma":0.000009259757,"domain_scores_codex":[0.9990638,0.00006475746,0.0001727111,0.0003923934,0.0001668197,0.0001395307],"domain_scores_gemma":[0.9995345,0.00004939282,0.00007524565,0.0002156141,0.00004643154,0.00007874795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002777063,0.000116941,0.0001194912,0.0001359805,0.00001959792,0.000007546055,0.0000392154,0.000001938344,0.9966148,0.0003049713,0.00004479823,0.002567002],"study_design_scores_gemma":[0.0002194868,0.001371813,0.005668597,0.0002679342,0.00002923634,0.000002654888,0.00001087683,0.001341712,0.9901645,0.0001310728,0.0006470436,0.0001450748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959207,0.0006118878,0.002591391,0.0001647983,0.0001418083,0.0003720818,0.0001335885,0.00001921415,0.00004459471],"genre_scores_gemma":[0.9992256,0.00005959922,0.0001475338,0.0001008764,0.00009295899,0.00006048413,0.0001250381,0.00001070631,0.0001772246],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00645025,"threshold_uncertainty_score":0.4457279,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005900087810604797,"score_gpt":0.2164277259600799,"score_spread":0.2105276381494751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}