{"id":"W4396740300","doi":"10.1016/j.eprac.2024.03.251","title":"#1783565 Double-Blind, Multiple Ascending Dose, Safety, Pharmacokinetic and Body Composition Study of Enobosarm in Healthy Young and Older Men","year":2024,"lang":"en","type":"article","venue":"Endocrine Practice","topic":"Analytical Methods in Pharmaceuticals","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Pharmacokinetics; Composition (language); Double blind; Internal medicine; Pathology; Placebo; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001424599,0.001401586,0.003164211,0.0005441165,0.0006684758,0.0006754581,0.0006938524,0.001207725,0.003957997],"category_scores_gemma":[0.001332824,0.0008128107,0.001178561,0.0003978251,0.001331377,0.001110394,0.000505365,0.001977367,0.0008779671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000428238,"about_ca_system_score_gemma":0.001259728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001424612,"about_ca_topic_score_gemma":0.002152135,"domain_scores_codex":[0.9992573,0.0003230888,0.00005847768,0.000173799,0.00008800467,0.00009934494],"domain_scores_gemma":[0.9990296,0.000176406,0.000184177,0.0001316549,0.00008614686,0.0003921185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9179542,0.02949518,0.005354243,0.0002715001,0.001326344,0.00008178042,0.0001420883,0.0003459251,0.02576348,0.00008206262,0.000600474,0.01858268],"study_design_scores_gemma":[0.3384672,0.5860552,0.06504001,0.00003969348,0.001363748,0.0001414343,0.0001250117,0.00101318,0.004841717,0.0001212886,0.002717987,0.00007359729],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956833,0.0009689626,0.0006532226,0.0001087315,0.0001381805,0.0009374872,0.000560973,0.0000851117,0.0008639717],"genre_scores_gemma":[0.9897001,0.0009429783,0.001328365,0.0007632794,0.0002580825,0.0008934592,0.0008603632,0.00004188751,0.005211603],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003957997,"threshold_uncertainty_score":0.01324081,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06320117028829099,"score_gpt":0.4496846505102063,"score_spread":0.3864834802219153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}