{"id":"W4396764089","doi":"10.1016/s0140-6736(24)00425-2","title":"Ductal carcinoma in situ of the breast: finding the balance between overtreatment and undertreatment","year":2024,"lang":"en","type":"review","venue":"The Lancet","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"Ductal carcinoma; Medicine; Breast cancer; Radiation therapy; Natural history; Oncology; Incidence (geometry); Internal medicine; Cancer; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001532451,0.0003636139,0.0009007536,0.00002377363,0.0001106699,0.00002622336,0.000425822,0.0001228827,0.000002469193],"category_scores_gemma":[0.00001187172,0.0001413536,0.0002526122,0.0001619426,0.0002077765,0.000001905069,0.0004813056,0.0001923944,0.000005653901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001208895,"about_ca_system_score_gemma":0.0001180702,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001502555,"about_ca_topic_score_gemma":0.0001934471,"domain_scores_codex":[0.9987661,0.0001756109,0.0002694288,0.0003738905,0.0001398955,0.0002750869],"domain_scores_gemma":[0.9989145,0.0000865547,0.0001622996,0.0008003471,0.00001367896,0.0000225593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002209713,0.0003707009,0.1711513,0.01389537,0.01107298,0.00009254918,0.002107228,0.000008491345,0.0001393394,0.001472794,0.02223822,0.77723],"study_design_scores_gemma":[0.002407033,0.0002422203,0.1806225,0.009204817,0.007925073,0.0009403403,0.0002671085,0.000002628168,0.0003845803,0.0006556432,0.7964961,0.0008519922],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01304013,0.9835855,6.454247e-7,0.001531287,0.0001484435,0.0006150578,0.0005057023,0.000006786983,0.000566474],"genre_scores_gemma":[0.2385087,0.7604601,0.000007868326,0.00004825429,0.0005641778,0.0001417827,0.00007109434,0.00002792873,0.0001700867],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.776378,"threshold_uncertainty_score":0.5764233,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0457482942612086,"score_gpt":0.320823427648177,"score_spread":0.2750751333869684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}