{"id":"W4396765528","doi":"10.1007/s13555-024-01155-7","title":"Triple Combination Clindamycin Phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% for Acne: Efficacy and Safety from a Pooled Phase 3 Analysis","year":2024,"lang":"en","type":"article","venue":"Dermatology and Therapy","topic":"Acne and Rosacea Treatments and Effects","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; Queen's University","funders":"National Center for Advancing Translational Sciences; Janssen Biotech; Allergan; LEO Pharma; Bausch Health; Regeneron Pharmaceuticals; Sun Pharma; Eli Lilly and Company; Ortho Dermatologics; Galderma; Sanofi Genzyme; Incyte; Dermira; Sanofi; Amgen; Pfizer","keywords":"Adapalene; Benzoyl peroxide; Acne; Clindamycin; Phosphate; Dermatology; Chemistry; Medicine; Pharmacology; Organic chemistry; Antibiotics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009186512,0.001064928,0.002964053,0.0007125404,0.0002944581,0.001436371,0.0005249137,0.0007975032,0.003865699],"category_scores_gemma":[0.005823459,0.0005504731,0.006602204,0.0007509646,0.0004851743,0.0008166765,0.0004889141,0.001109786,0.0004920207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007319245,"about_ca_system_score_gemma":0.001618787,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006988215,"about_ca_topic_score_gemma":0.002352456,"domain_scores_codex":[0.9972145,0.001608571,0.0002912235,0.0003357467,0.0004232649,0.0001266784],"domain_scores_gemma":[0.9962294,0.001236786,0.001371138,0.0003912745,0.0005097573,0.0002617932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.6801423,0.005388771,0.0119417,0.01347042,0.1136046,0.0001497635,0.0003376133,0.002313697,0.0261049,0.0002626578,0.003532568,0.142751],"study_design_scores_gemma":[0.4697653,0.2604952,0.06527548,0.001974816,0.1785216,0.0005626836,0.0002242905,0.002297255,0.008525809,0.0007113804,0.01146252,0.0001836542],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8690671,0.1051264,0.007736654,0.0006868643,0.0004108438,0.007524053,0.005491591,0.000335457,0.00362091],"genre_scores_gemma":[0.9769315,0.01420922,0.002910997,0.0004932639,0.0001768758,0.002475316,0.001685944,0.00005405752,0.001062655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009186512,"threshold_uncertainty_score":0.04858345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01505356341424612,"score_gpt":0.318222111265921,"score_spread":0.3031685478516749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}