{"id":"W4396765528","doi":"10.1007/s13555-024-01155-7","title":"Triple Combination Clindamycin Phosphate 1.2%/Adapalene 0.15%/Benzoyl Peroxide 3.1% for Acne: Efficacy and Safety from a Pooled Phase 3 Analysis","year":2024,"lang":"en","type":"article","venue":"Dermatology and Therapy","topic":"Acne and Rosacea Treatments and Effects","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; Queen's University","funders":"National Center for Advancing Translational Sciences; Janssen Biotech; Allergan; LEO Pharma; Bausch Health; Regeneron Pharmaceuticals; Sun Pharma; Eli Lilly and Company; Ortho Dermatologics; Galderma; Sanofi Genzyme; Incyte; Dermira; Sanofi; Amgen; Pfizer","keywords":"Adapalene; Benzoyl peroxide; Acne; Clindamycin; Phosphate; Dermatology; Chemistry; Medicine; Pharmacology; Organic chemistry; Antibiotics; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001114673,0.0001827553,0.000514239,0.0001591185,0.0001752471,0.00003594927,0.00003166781,0.0001697361,0.0001067981],"category_scores_gemma":[0.00001581084,0.0001271841,0.000133341,0.0002187141,0.00007870483,0.00007819015,0.0000118538,0.0001101538,0.0000092277],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001204987,"about_ca_system_score_gemma":0.00003414475,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003632736,"about_ca_topic_score_gemma":0.000008242289,"domain_scores_codex":[0.9990901,0.0000609666,0.0002375506,0.0003396234,0.00007158153,0.0002001406],"domain_scores_gemma":[0.9993508,0.0003159893,0.00004715203,0.0001445225,0.00003391504,0.0001076458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.02459264,0.004123366,0.0735793,0.0005144608,0.03048972,0.001237386,0.005950697,0.000007723062,0.02108913,0.005977926,0.005598519,0.8268391],"study_design_scores_gemma":[0.2867446,0.007232407,0.242853,0.0007268892,0.02217536,0.00111761,0.0007932041,0.07942925,0.1276193,0.008529837,0.2209997,0.001778823],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9553759,0.03831343,0.002234376,0.003075094,0.000160764,0.0006242334,0.00007915844,0.0000661961,0.00007090074],"genre_scores_gemma":[0.990372,0.007659538,0.000213758,0.0008415515,0.00004910543,0.00004029451,0.0004597012,0.00001808022,0.0003459819],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8250603,"threshold_uncertainty_score":0.5186419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01505356341424612,"score_gpt":0.318222111265921,"score_spread":0.3031685478516749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}