{"id":"W4396768709","doi":"10.7554/elife.86354.sa2","title":"Author response: MEMO1 binds iron and modulates iron homeostasis in cancer cells","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Iron homeostasis; Homeostasis; Cancer cell; Cancer; Chemistry; Cell biology; Biology; Cancer research; Biochemistry; Genetics; Metabolism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004504016,0.0005357111,0.0006327034,0.001289571,0.001365146,0.003290989,0.00107393,0.003720353,0.1492057],"category_scores_gemma":[0.0397752,0.0002679734,0.0003671301,0.0005701937,0.001236582,0.001303627,0.002301068,0.002598072,0.04699894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001326747,"about_ca_system_score_gemma":0.00452688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001405311,"about_ca_topic_score_gemma":0.002863768,"domain_scores_codex":[0.9961666,0.001001846,0.0002106153,0.0003781777,0.001863422,0.0003791448],"domain_scores_gemma":[0.9621118,0.006401996,0.001845504,0.001425814,0.02293346,0.005281297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001937789,0.00002265283,0.0007810603,0.0004007628,0.00002093414,0.0003026533,0.0002319888,0.00006168986,0.0018048,0.001732894,0.9590647,0.03538205],"study_design_scores_gemma":[0.00004509783,0.0000525649,0.001298208,0.000176336,0.00001272508,0.000358198,0.0005173124,0.00009974286,0.001706082,0.001431255,0.9942814,0.00002104912],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.0108885,0.01126688,0.002909685,0.5645446,0.3069307,0.0003389939,0.002950964,0.001097282,0.09907252],"genre_scores_gemma":[0.05335585,0.01217916,0.003028623,0.08296625,0.0700933,0.0002010093,0.002639269,0.0008026092,0.774734],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.8507943,"threshold_uncertainty_score":0.4991428,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04373125773694524,"score_gpt":0.3569479937825542,"score_spread":0.313216736045609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}