{"id":"W4396790575","doi":"10.1016/j.cofs.2024.101174","title":"Soluble epoxide hydrolase: an emerging target for nutraceuticals against inflammation and oxidative stress","year":2024,"lang":"en","type":"article","venue":"Current Opinion in Food Science","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; University of Ottawa","keywords":"Oxidative stress; Epoxide hydrolase 2; Epoxide; Nutraceutical; Epoxide hydrolase; Inflammation; Chemistry; Oxidative phosphorylation; Biochemistry; Biology; Enzyme; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006002694,0.0005996012,0.001140028,0.0003733675,0.0001976775,0.00138663,0.0004789246,0.001582661,0.003612183],"category_scores_gemma":[0.0003227893,0.0001276237,0.0003358206,0.0003975823,0.0006879,0.001795082,0.0005407832,0.002124914,0.001382102],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000402117,"about_ca_system_score_gemma":0.0008032611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000251823,"about_ca_topic_score_gemma":0.0006133225,"domain_scores_codex":[0.9998726,0.000015151,0.0000112641,0.00003460268,0.00003755143,0.00002877211],"domain_scores_gemma":[0.9997346,0.000052457,0.00005540743,0.00000883156,0.00009018265,0.00005848374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001965928,0.0004883805,0.001865503,0.005348127,0.0001713326,0.001459153,0.0002108078,0.0007065051,0.2204432,0.0179215,0.0379949,0.7114246],"study_design_scores_gemma":[0.0005011138,0.003186745,0.007802666,0.001432595,0.0004833589,0.003112368,0.001091089,0.002758763,0.04358764,0.03196405,0.9039752,0.000104491],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02573192,0.9269487,0.01001828,0.02637697,0.003226391,0.00005598097,0.0003752488,0.0001509474,0.007115473],"genre_scores_gemma":[0.08251293,0.8926129,0.005722228,0.005638412,0.004247575,0.00007062771,0.0004849606,0.00002566815,0.008684698],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003612183,"threshold_uncertainty_score":0.01208401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06367124244138554,"score_gpt":0.3892666568692292,"score_spread":0.3255954144278437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}