{"id":"W4396801928","doi":"10.51731/cjht.2024.890","title":"Inclisiran (Leqvio)","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Statin; Internal medicine; Atherosclerotic cardiovascular disease; Clinical trial; Cause of death; Drug; Adverse effect; Disease; Cholesterol; Quality of life (healthcare); Pharmacology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001804855,0.0004206923,0.0009262286,0.001053433,0.0004982318,0.00177328,0.001882386,0.002893807,0.03260595],"category_scores_gemma":[0.003397418,0.000232415,0.001013776,0.0006503202,0.0004581561,0.001116412,0.0009498345,0.004054653,0.01042062],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001230381,"about_ca_system_score_gemma":0.00241391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003318207,"about_ca_topic_score_gemma":0.009744875,"domain_scores_codex":[0.9990917,0.0002547666,0.00009651516,0.0001629919,0.0002657889,0.0001282537],"domain_scores_gemma":[0.9987773,0.0003132123,0.0002740545,0.0001058078,0.0002310435,0.0002985013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.01179908,0.000974854,0.002062952,0.002746882,0.0002693312,0.0005357608,0.0001313909,0.000382009,0.005110077,0.009445293,0.194023,0.7725194],"study_design_scores_gemma":[0.01706367,0.002870919,0.00461835,0.001984853,0.0003346276,0.001283813,0.00007638354,0.0003735933,0.00205137,0.002867662,0.9664198,0.00005494365],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"other","genre_gemma":"other","genre_scores_codex":[0.07099013,0.2402064,0.006344196,0.08313246,0.006368237,0.003310709,0.02210891,0.004986241,0.5625528],"genre_scores_gemma":[0.3770829,0.1116411,0.02270717,0.1611129,0.003740015,0.004267368,0.03698086,0.0008306809,0.2816369],"genre_candidate":"other","genre_consensus":"other","teacher_disagreement_score":0.03260595,"threshold_uncertainty_score":0.1090778,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0239716322360526,"score_gpt":0.2909063719189848,"score_spread":0.2669347396829322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}