{"id":"W4396814128","doi":"10.1136/bmjresp-2023-001995","title":"Extracorporeal photopheresis (ECP) in the treatment of chronic lung allograft dysfunction (CLAD): a prospective, multicentre, open-label, randomised controlled trial studying the addition of ECP to standard care in the treatment of bilateral lung transplant patients with CLAD (E-CLAD UK)","year":2024,"lang":"en","type":"article","venue":"BMJ Open Respiratory Research","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Efficacy and Mechanism Evaluation Programme; National Institute for Health and Care Research; Mallinckrodt Pharmaceuticals","keywords":"Medicine; Extracorporeal Photopheresis; Photopheresis; Open label; Randomized controlled trial; Standard of care; Extracorporeal; Surgery; Internal medicine; Graft-versus-host disease; Transplantation; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002667656,0.00126026,0.002509492,0.0004199268,0.0004474197,0.001017633,0.0009051994,0.002247584,0.005337747],"category_scores_gemma":[0.002650322,0.0005805876,0.001871849,0.0004014588,0.001300185,0.001018578,0.0005393943,0.002200085,0.0006107338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007569365,"about_ca_system_score_gemma":0.001427165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001138527,"about_ca_topic_score_gemma":0.002468885,"domain_scores_codex":[0.9987254,0.0007964327,0.00009219519,0.0001616013,0.00007955821,0.0001449068],"domain_scores_gemma":[0.9981284,0.0006144836,0.0004742809,0.0001080795,0.0001173795,0.0005574874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9833503,0.007048561,0.0004243503,0.0007221471,0.0003419536,0.00002321723,0.00003008794,0.0001241364,0.001034415,0.00004245889,0.0001552873,0.006703224],"study_design_scores_gemma":[0.9149922,0.08288786,0.001289602,0.0000450978,0.0002385903,0.00001791415,0.00001433727,0.0001156838,0.0001643866,0.00003250395,0.0001950139,0.000006878532],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985324,0.004678518,0.0003990466,0.0004531834,0.0004040811,0.006983595,0.0004693588,0.00004146028,0.001246813],"genre_scores_gemma":[0.9861869,0.002536358,0.001560353,0.0007399617,0.0004061238,0.006605039,0.0004201604,0.00000723575,0.001537982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005337747,"threshold_uncertainty_score":0.01785654,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1174491365186445,"score_gpt":0.4555211839836674,"score_spread":0.338072047465023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}