{"id":"W4396830919","doi":"10.1016/j.synbio.2024.05.006","title":"New N-acylated aminoalkanoic acids from tea roots derived biocontrol agent Clonostachys rosea 15020","year":2024,"lang":"en","type":"article","venue":"Synthetic and Systems Biotechnology","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"National Key Research and Development Program of China; Higher Education Discipline Innovation Project; State Key Laboratory of Bioreactor Engineering; National Natural Science Foundation of China","keywords":"Polyketide; Moiety; Stereochemistry; Chemistry; Amide; Side chain; Enzyme; Biochemistry; Organic chemistry; Biosynthesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002112805,0.0003707978,0.0007481737,0.0003299869,0.0001150528,0.000122124,0.000190964,0.0007574996,0.00009344165],"category_scores_gemma":[0.0001756774,0.0002589897,0.0001421523,0.0003674988,0.000229337,0.00006239668,0.0001196047,0.0005129003,0.0002242229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009456942,"about_ca_system_score_gemma":0.0001283944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001373725,"about_ca_topic_score_gemma":0.00001371334,"domain_scores_codex":[0.9978636,0.00008343958,0.0005130849,0.0008715955,0.0001819133,0.0004863502],"domain_scores_gemma":[0.998941,0.0001031345,0.00009191082,0.0005987854,0.00004983748,0.00021533],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001028201,0.00003434864,0.00009957324,0.0001999438,0.0002794516,0.000218789,0.00007332036,4.330326e-7,0.9291788,0.0009112147,0.001142127,0.06775922],"study_design_scores_gemma":[0.0009281397,0.0004278999,0.0008009787,0.0005397201,0.0004137977,0.0007573374,0.000289538,0.001279842,0.8680769,0.0001975684,0.125852,0.0004363125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9220488,0.05038799,0.001520602,0.02127441,0.001884125,0.001319145,0.0002530705,0.001062174,0.0002496425],"genre_scores_gemma":[0.9958703,0.000946875,0.0004240898,0.000138454,0.0004216575,0.000006978943,0.00007266422,0.00005038703,0.002068626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1247099,"threshold_uncertainty_score":0.9999862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01046657521990131,"score_gpt":0.2301221347380505,"score_spread":0.2196555595181492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}