{"id":"W4396841769","doi":"10.1097/olq.0000000000001962","title":"Response to Antibiotic Treatment of Bacterial Vaginosis Predicts the Effectiveness of LACTIN-V (Lactobacillus crispatus CTV-05) in the Prevention of Recurrent Disease","year":2024,"lang":"en","type":"article","venue":"Sexually Transmitted Diseases","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Medicine; Bacterial vaginosis; Metronidazole; Lactobacillus crispatus; Placebo; Internal medicine; Antibiotics; Confidence interval; Clinical trial; Regimen; Vaginal disease; Vaginal flora; Gastroenterology; Surgery; Vagina; Lactobacillus; Gynecology; Microbiology; Bacteria; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004701553,0.0004497825,0.00070037,0.0002695527,0.0001460329,0.0005544797,0.0003203685,0.00070215,0.001979781],"category_scores_gemma":[0.01030775,0.0002386382,0.001076137,0.000207645,0.0002929832,0.0003578027,0.0002991046,0.00107925,0.0002101378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002364408,"about_ca_system_score_gemma":0.0003227416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005927727,"about_ca_topic_score_gemma":0.0005883295,"domain_scores_codex":[0.9976341,0.001398648,0.0001545397,0.0003316746,0.0003292988,0.0001517627],"domain_scores_gemma":[0.9891901,0.006507159,0.002980998,0.0003779816,0.0002734363,0.0006702459],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.2075934,0.003192851,0.7190733,0.000714638,0.004863087,0.00006345883,0.0001400509,0.001375336,0.009444911,0.00009713113,0.0005438406,0.05289802],"study_design_scores_gemma":[0.002681468,0.03487545,0.9545501,0.0001151179,0.001594169,0.0001131284,0.00006724583,0.003460978,0.001936233,0.00009130059,0.0004967193,0.00001810535],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968991,0.001876998,0.0002823139,0.0001258224,0.00003053921,0.00008035404,0.0002039621,0.000008219947,0.0004927453],"genre_scores_gemma":[0.9991066,0.0001984277,0.000237153,0.00004553993,0.00002197745,0.00003144145,0.0001837363,0.000002410198,0.0001725448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004701553,"threshold_uncertainty_score":0.02486449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02011827452309944,"score_gpt":0.3118108421531623,"score_spread":0.2916925676300628,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}