{"id":"W4396860492","doi":"10.5334/tohm.886","title":"Validation of a New Patient-Reported Outcome Measure of the Functional Impact of Essential Tremor on Activities of Daily Living","year":2024,"lang":"en","type":"article","venue":"Tremor and Other Hyperkinetic Movements","topic":"Neurological disorders and treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Brain Institute; Toronto Western Hospital; University of Toronto","funders":"Dystonia Coalition; Parkinsonfonden; Ipsen; Parkinson's Foundation; Neurocrine Biosciences; National Organization for Rare Disorders; Barrow Neurological Foundation; Boston Scientific Corporation; Jazz Pharmaceuticals; National Institute of Neurological Disorders and Stroke; Teva Pharmaceutical Industries; National Institutes of Health; Sage Therapeutics; Biogen; International Essential Tremor Foundation; Michael J. Fox Foundation for Parkinson's Research","keywords":"Activities of daily living; Essential tremor; Rating scale; Scale (ratio); Physical therapy; Psychology; Physical medicine and rehabilitation; Medicine; Outcome (game theory); Gerontology; Developmental psychology; Cartography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005550704,0.0001224942,0.0002950638,0.00008005568,0.00001415664,0.000003849918,0.00003626611,0.00004078733,0.0003982505],"category_scores_gemma":[0.00004421765,0.00006833157,0.0001818894,0.0001310122,0.00006729595,0.00002380287,0.00002353962,0.00005601656,5.033266e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001273967,"about_ca_system_score_gemma":0.00004835835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000326838,"about_ca_topic_score_gemma":0.000003717723,"domain_scores_codex":[0.9990208,0.0000347514,0.0003616409,0.0001572492,0.000335363,0.00009022334],"domain_scores_gemma":[0.9995022,0.00006539376,0.0001857305,0.0001751375,0.00003392649,0.00003755601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007475266,0.001174947,0.832619,0.0002854569,0.0009059408,0.000006548325,0.0008162271,0.00008049917,0.1473379,0.00004260306,0.0002227815,0.01576066],"study_design_scores_gemma":[0.001732894,0.001462755,0.9481324,0.0003434526,0.0003454721,0.000004811626,0.0001038051,0.0001459949,0.0474222,0.0002219211,0.00002171998,0.00006258536],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998129,0.0002199856,0.00002876714,0.0000468303,0.0001005725,0.0002888746,0.0000345618,0.000007793959,0.001143691],"genre_scores_gemma":[0.9992219,0.000007449426,0.00002559055,0.00008212539,0.00001957555,0.000003272876,0.000003686273,0.00001394252,0.0006225173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1155134,"threshold_uncertainty_score":0.4360563,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0477727799733409,"score_gpt":0.2935242912162793,"score_spread":0.2457515112429384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}