{"id":"W4396872827","doi":"10.1073/pnas.2401748121","title":"The 6-kilodalton peptide 1 in plant viruses of the family Potyviridae is a viroporin","year":2024,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Plant Virus Research Studies","field":"Agricultural and Biological Sciences","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"National Key Research and Development Program of China; Heilongjiang Provincial Science and Technology Department; Nanjing Agricultural University; Northeast Agricultural University; Centro Nacional de Biotecnología; Natural Science Foundation of Heilongjiang Province; National Natural Science Foundation of China","keywords":"Potyviridae; Nicotiana benthamiana; Biology; Endoplasmic reticulum; Tetraspanin; Peptide; Potyvirus; Plant virus; Cell biology; Biochemistry; Virology; Virus; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001757815,0.0000909352,0.0001322583,0.0000393235,0.0003733058,0.00005578555,0.001378487,0.00005120529,0.00001043875],"category_scores_gemma":[0.0005543185,0.00002188039,0.0001026934,0.001345483,0.001273588,0.0002401706,0.0003818226,0.0002212509,0.000002311053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002991244,"about_ca_system_score_gemma":0.00002548733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001737325,"about_ca_topic_score_gemma":0.0000123063,"domain_scores_codex":[0.9978341,0.00001783709,0.0003188407,0.0002152694,0.001405966,0.0002080212],"domain_scores_gemma":[0.9989521,0.0007196153,0.0001869549,0.000006023426,0.0001138263,0.00002150338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001756113,0.00002331229,0.00556656,0.00002717549,0.00001328897,1.56266e-8,0.000184387,0.000005656924,0.9742161,0.01143297,0.007172517,0.001340436],"study_design_scores_gemma":[0.00005157004,0.00007652131,0.5588903,0.0002977135,0.000006932297,0.000004725467,0.0009816797,0.0004477869,0.3915186,0.02718476,0.02044972,0.00008970173],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833333,0.0011215,7.229058e-9,0.0121003,0.00003081577,0.0001872697,0.0002649502,0.000008275544,0.002953596],"genre_scores_gemma":[0.9987432,0.000567972,0.00001605773,0.0003547941,0.00006561076,0.00001223457,1.2636e-7,4.891891e-7,0.0002395529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5826976,"threshold_uncertainty_score":0.4692589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08414527545855933,"score_gpt":0.3179327599069209,"score_spread":0.2337874844483616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}