{"id":"W4396887307","doi":"10.1038/s41467-024-47632-7","title":"A burden of proof study on alcohol consumption and ischemic heart disease","year":2024,"lang":"en","type":"review","venue":"Nature Communications","topic":"Alcohol Consumption and Health Effects","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Ontario; University of Toronto; Centre for Addiction and Mental Health","funders":"Centers for Disease Control and Prevention; NIHR Oxford Biomedical Research Centre; University of Oxford; British Heart Foundation; Medical Research Council; Centers for Disease Control and Prevention Foundation; World Health Organization; National Institute for Health and Care Research; Bill and Melinda Gates Foundation","keywords":"Alcohol consumption; Disease; Proof of concept; Burden of disease; Burden of proof; Medicine; Environmental health; Consumption (sociology); Cardiology; Computer science; Alcohol; Internal medicine; Intensive care medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0003954538,0.0003069048,0.001116076,0.000377391,0.0001297397,0.00002162769,0.0003381154,0.0004478234,0.00002221163],"category_scores_gemma":[0.0003198096,0.0002320757,0.0002319282,0.0003106508,0.0001833441,0.00003133091,0.0003071926,0.00248879,0.000153082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000115971,"about_ca_system_score_gemma":0.0004766993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007085748,"about_ca_topic_score_gemma":0.00001305974,"domain_scores_codex":[0.9982924,0.0003494932,0.000552856,0.0003657654,0.0002797894,0.0001597347],"domain_scores_gemma":[0.9966663,0.0005138797,0.0002188932,0.002227048,0.0001299868,0.000243963],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003993522,0.004955834,0.004457217,0.2996759,0.002542032,0.00007463739,0.002262776,2.575202e-7,0.00004139399,0.006555002,0.1139354,0.5651001],"study_design_scores_gemma":[0.0004812655,0.0001766094,0.00153414,0.02155052,0.004250418,0.00004006414,0.00003702638,0.0000173224,3.52346e-7,0.000008285334,0.9717342,0.0001698384],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000392989,0.9920067,4.189458e-7,0.002287457,0.0001236288,0.004540093,0.0001064943,0.00008474639,0.0004574696],"genre_scores_gemma":[0.03932258,0.9586773,0.0001497191,0.0003268727,0.00008281626,0.0006647794,0.0003550914,0.00005251277,0.000368316],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8577987,"threshold_uncertainty_score":0.9998125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2202120360651926,"score_gpt":0.5069592560104844,"score_spread":0.2867472199452918,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}