{"id":"W4396894671","doi":"10.1093/nar/gkae347","title":"Riboswitch and small RNAs modulate <i>btuB</i> translation initiation in <i>Escherichia coli</i> and trigger distinct mRNA regulatory mechanisms","year":2024,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"H2020 European Research Council; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; College of Natural Resources and Sciences, Humboldt State University; Agence Nationale de la Recherche","keywords":"Riboswitch; Biology; RNA; Genetics; Non-coding RNA; Regulation of gene expression; Gene expression; Messenger RNA; Transfer RNA; Translation (biology); Gene; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007322201,0.0002411332,0.000168168,0.00008714593,0.00009334066,0.0002680215,0.0001041358,0.0001782519,0.0005164173],"category_scores_gemma":[0.0001019923,0.00008305475,0.0001654332,0.00007481725,0.0001556614,0.000103775,0.0001192572,0.0002762216,0.0001633771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002570224,"about_ca_system_score_gemma":0.0001152917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004991878,"about_ca_topic_score_gemma":0.0008960437,"domain_scores_codex":[0.9998883,0.00001477058,0.00000682421,0.00002579397,0.00002934156,0.00003497578],"domain_scores_gemma":[0.9999433,0.00001432608,0.00001688392,0.000005280777,0.000006883216,0.00001330931],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000373414,0.00000964117,0.0001061024,0.000009137108,0.000001421599,0.00001231081,0.000003522105,0.00005024188,0.9992431,0.0000588251,0.000008524612,0.0004598646],"study_design_scores_gemma":[0.00000322155,0.00007720586,0.002165266,0.000001212727,0.000003517811,0.0000210932,0.00001007381,0.0009566065,0.9964111,0.00002909735,0.0003186387,0.000002896453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949775,0.0003447981,0.003012694,0.00004020754,0.0000148264,0.00001639693,0.0001132809,0.00007666279,0.001403489],"genre_scores_gemma":[0.9970988,0.0001554301,0.001528431,0.00005733642,0.00000397047,0.00001812967,0.0001263487,0.00002447784,0.0009871611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005164173,"threshold_uncertainty_score":0.001864791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03601164322718803,"score_gpt":0.2918169168519271,"score_spread":0.255805273624739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}