{"id":"W4396901149","doi":"10.1101/2024.05.13.593962","title":"Differential roles of putative arginine fingers of AAA <sup>+</sup> ATPases Rvb1 and Rvb2","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Office of Advanced Cyberinfrastructure; University of Toronto; Emory University; National Institutes of Health; National Science Foundation","keywords":"Biogenesis; AAA proteins; Biology; ATP hydrolysis; ATPase; Arginine; Binding site; Cell biology; Chromatin remodeling; Computational biology; Biochemistry; Chromatin; Amino acid; DNA; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002287848,0.0003033541,0.0003993777,0.0001338839,0.0001633458,0.0004460121,0.0004014249,0.0004692736,0.0007399276],"category_scores_gemma":[0.0002917692,0.0001820636,0.0002504058,0.0001011026,0.0002537455,0.0002579405,0.0002549884,0.0003669906,0.0003320986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002407027,"about_ca_system_score_gemma":0.0001207631,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005455033,"about_ca_topic_score_gemma":0.0003823764,"domain_scores_codex":[0.9998425,0.00003136661,0.00001294718,0.00004102147,0.00004693358,0.00002515453],"domain_scores_gemma":[0.9998406,0.0000373373,0.0000515016,0.000009829017,0.00001483223,0.00004594857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002920847,0.00003329427,0.002288783,0.00003995388,0.00001413432,0.0001153531,0.00002528454,0.001266065,0.9944044,0.000316188,0.00003780179,0.001166572],"study_design_scores_gemma":[0.0001445017,0.0004377704,0.04325389,0.0000215527,0.00005420421,0.001325333,0.000186575,0.07729097,0.8736817,0.0004819154,0.003056678,0.0000649005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977885,0.0003393657,0.001476606,0.00002215313,0.000008482025,0.000004736421,0.00005106318,0.00001964972,0.0002894947],"genre_scores_gemma":[0.9987296,0.00005157415,0.000948916,0.00001227041,0.000002017591,0.000005199782,0.0000808697,0.000007737063,0.0001617864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007399276,"threshold_uncertainty_score":0.002475321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009674483549184392,"score_gpt":0.2385917346380037,"score_spread":0.2289172510888193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}