{"id":"W4396926569","doi":"10.3390/microorganisms12050991","title":"Secreted Metabolites from Pseudomonas, Staphylococcus, and Borrelia Biofilm: Modulation of Immunogenicity by a Nutraceutical Enzyme and Botanical Blend","year":2024,"lang":"en","type":"article","venue":"Microorganisms","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dover (Canada)","funders":"","keywords":"Biofilm; Microbiology; Immune system; Immunogenicity; Biology; Nutraceutical; Cytokine; Inflammation; Tumor necrosis factor alpha; Immunology; Bacteria; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001438942,0.0003749244,0.0002409062,0.0001992156,0.00008198684,0.000244329,0.00009221698,0.0002204762,0.0005244416],"category_scores_gemma":[0.0001544495,0.0001092337,0.0002356875,0.0001428847,0.0001089563,0.0001852116,0.0001965699,0.0003193741,0.0001052048],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008705822,"about_ca_system_score_gemma":0.0001138643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001714773,"about_ca_topic_score_gemma":0.0003564265,"domain_scores_codex":[0.9998928,0.00002405714,0.000009023216,0.00001997004,0.00003774669,0.00001633738],"domain_scores_gemma":[0.9999219,0.00001397128,0.00002502535,0.00000715133,0.0000130141,0.00001888105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008665698,0.00003300018,0.0001257645,0.00002609429,0.000002389679,0.0000126828,0.000004272326,0.00001554753,0.9990838,0.000004267542,0.000002856639,0.00060259],"study_design_scores_gemma":[0.00002537485,0.00230645,0.009511883,0.00001258033,0.0000319095,0.0001398139,0.00003973403,0.0002161574,0.9868456,0.00001948847,0.0008451198,0.000005793489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976128,0.001029811,0.0008633828,0.00003535911,0.00001164353,0.00003001181,0.0001336026,0.000009925331,0.0002735431],"genre_scores_gemma":[0.9943356,0.000966901,0.003454225,0.0000543116,0.00001008321,0.00004512921,0.0002896907,0.000009104328,0.0008349027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005244416,"threshold_uncertainty_score":0.001754403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005695632490395082,"score_gpt":0.2215456862908701,"score_spread":0.215850053800475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}