{"id":"W4396926569","doi":"10.3390/microorganisms12050991","title":"Secreted Metabolites from Pseudomonas, Staphylococcus, and Borrelia Biofilm: Modulation of Immunogenicity by a Nutraceutical Enzyme and Botanical Blend","year":2024,"lang":"en","type":"article","venue":"Microorganisms","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dover (Canada)","funders":"","keywords":"Biofilm; Microbiology; Immune system; Immunogenicity; Biology; Nutraceutical; Cytokine; Inflammation; Tumor necrosis factor alpha; Immunology; Bacteria; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001197928,0.0001938102,0.000230759,0.00002849429,0.00005955719,0.00008424191,0.00007133491,0.0002631324,0.00003518694],"category_scores_gemma":[0.00002693588,0.0001777885,0.00006002004,0.00008273919,0.0001699201,0.000009694148,0.0001261776,0.0001163445,0.000003071541],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007992461,"about_ca_system_score_gemma":0.00003657142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001691516,"about_ca_topic_score_gemma":0.00001380662,"domain_scores_codex":[0.9989221,0.00005895369,0.0002737387,0.0004489699,0.00008283791,0.0002134096],"domain_scores_gemma":[0.9995856,0.0000278896,0.00004898528,0.0002036619,0.00004087213,0.00009293904],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008374066,0.00002857665,0.0003801233,0.00002538428,0.0001136648,0.000002741447,0.00005526566,1.638488e-7,0.9968599,0.0001160825,0.00061224,0.001722114],"study_design_scores_gemma":[0.0003692114,0.000120589,0.00440316,0.00002843804,0.00007552699,0.00001822074,0.00003662916,0.0001676474,0.9827271,0.00009864404,0.0117516,0.0002032112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9734909,0.02500059,0.0004374228,0.000203878,0.0001518461,0.0001343804,0.0005458345,0.00002310864,0.00001202832],"genre_scores_gemma":[0.9959639,0.0009395775,0.002387695,0.00009565915,0.0001403437,0.000001825405,0.0003953071,0.000030934,0.00004477227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02406101,"threshold_uncertainty_score":0.7250006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005695632490395082,"score_gpt":0.2215456862908701,"score_spread":0.215850053800475,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}