{"id":"W4396930326","doi":"10.1002/acr2.11669","title":"Upadacitinib in Active Non‐radiographic Axial Spondyloarthritis: <scp>1‐Year</scp> Data From a <scp>Double‐Blind</scp>, Randomized, <scp>Placebo‐Controlled</scp>, Phase 3 Trial","year":2024,"lang":"en","type":"article","venue":"ACR Open Rheumatology","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"AbbVie Canada","keywords":"Placebo; Medicine; Double blind; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002102565,0.0006002637,0.001354453,0.0001828149,0.0003585327,0.0007544057,0.0004020101,0.0006487666,0.002930144],"category_scores_gemma":[0.001430193,0.0002343813,0.001531443,0.0003626732,0.000351481,0.0004162224,0.0002203997,0.001437552,0.0003941865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004743474,"about_ca_system_score_gemma":0.0009845317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009152513,"about_ca_topic_score_gemma":0.003948153,"domain_scores_codex":[0.9993924,0.0003270587,0.00005361997,0.00007909402,0.00008452032,0.00006340285],"domain_scores_gemma":[0.9989598,0.0002354711,0.0004261488,0.00007534303,0.0001364757,0.0001667624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8706797,0.004566333,0.01053855,0.003633262,0.006311472,0.0001474148,0.0001350264,0.001714273,0.008916217,0.0001886822,0.007047506,0.0861215],"study_design_scores_gemma":[0.8356539,0.09261645,0.05568668,0.0003568613,0.005366439,0.0004860087,0.00007384429,0.001484024,0.002992961,0.0002312552,0.005001811,0.00004985103],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787012,0.01208185,0.0006552572,0.0006388445,0.0001898079,0.001489989,0.003976224,0.00007630415,0.002190525],"genre_scores_gemma":[0.9886712,0.004295365,0.0008057827,0.0004537963,0.0001077028,0.001094508,0.003486537,0.00001132682,0.001073859],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002930144,"threshold_uncertainty_score":0.0111196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04687363893128597,"score_gpt":0.3504996081643227,"score_spread":0.3036259692330368,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}