{"id":"W4396932885","doi":"10.1002/mlf2.12108","title":"Dual activities of a silencing information regulator complex in yeast transcriptional regulation and DNA‐damage response","year":2024,"lang":"en","type":"article","venue":"mLife","topic":"Sirtuins and Resveratrol in Medicine","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; University of Alberta","keywords":"Regulator; Gene silencing; DNA damage; Transcriptional regulation; Cell biology; DNA; Yeast; Dual (grammatical number); Biology; Genetics; Computational biology; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002392793,0.0005884506,0.0005196277,0.0005505164,0.0002750802,0.0006596989,0.000331267,0.0005003175,0.001409727],"category_scores_gemma":[0.00009389324,0.0001910453,0.0004557141,0.0003946908,0.0003076439,0.0003550429,0.0003880604,0.00056557,0.000976275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005850053,"about_ca_system_score_gemma":0.0004153678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000684484,"about_ca_topic_score_gemma":0.0009194876,"domain_scores_codex":[0.9998125,0.00002937697,0.00002050174,0.00005241148,0.00006005179,0.00002509096],"domain_scores_gemma":[0.9999405,0.000007987292,0.00001431629,0.000006816929,0.00001663226,0.00001362782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003295029,0.00002774989,0.0006857039,0.001814734,0.00008538883,0.0008271187,0.0002379459,0.0004614301,0.9203339,0.007866992,0.001665965,0.06566361],"study_design_scores_gemma":[0.00004892022,0.0003459978,0.009880937,0.000230232,0.0002623043,0.004101925,0.0002603045,0.001354466,0.6069415,0.002593252,0.3739122,0.0000680277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1869719,0.7008251,0.06377524,0.001425961,0.001388265,0.0001592656,0.001837814,0.0015359,0.04208067],"genre_scores_gemma":[0.7713588,0.1712218,0.01982978,0.0006091998,0.0003404011,0.00009705603,0.004062422,0.0001508022,0.0323297],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001409727,"threshold_uncertainty_score":0.004716039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01793175452455067,"score_gpt":0.2684061722271492,"score_spread":0.2504744177025985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}