{"id":"W4396955393","doi":"10.3390/bioengineering11050494","title":"Navigating the Immunological Crossroads: Mesenchymal Stem/Stromal Cells as Architects of Inflammatory Harmony in Tissue-Engineered Constructs","year":2024,"lang":"en","type":"review","venue":"Bioengineering","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mesenchymal stem cell; Stromal cell; Immune system; Paracrine signalling; Regeneration (biology); Stem cell; Regenerative medicine; Microcarrier; Medicine; Inflammation; Immunology; Biology; Cell biology; Cancer research; Cell; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009757747,0.0008241308,0.002353549,0.000386906,0.0000640634,0.00009965187,0.0006778631,0.0006402509,0.0001041996],"category_scores_gemma":[0.0003163602,0.0005390827,0.0005470216,0.00121742,0.0003569515,0.00006496726,0.0005421144,0.003773253,0.0003221047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003527107,"about_ca_system_score_gemma":0.0006916828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000651091,"about_ca_topic_score_gemma":0.000002446187,"domain_scores_codex":[0.9956273,0.0002059186,0.001543065,0.0007401253,0.0008822031,0.001001336],"domain_scores_gemma":[0.9978494,0.0006555329,0.0002596317,0.0008671755,0.0001003121,0.0002679594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005296731,0.00008934298,0.00002664646,0.1002398,0.0007474064,0.002855263,0.0005205306,0.0001925874,0.0236976,0.0005067139,0.0001978371,0.8708733],"study_design_scores_gemma":[0.001385725,0.000919228,0.0001071984,0.15541,0.001381314,0.003174116,0.0003944716,0.001019201,0.01570512,0.00002658414,0.8188866,0.001590495],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02694374,0.9693509,0.00002631384,0.00008009927,0.0006560057,0.002111328,0.00004834486,0.0001905824,0.000592661],"genre_scores_gemma":[0.01641945,0.981191,0.0005831507,0.000009063519,0.0003747196,0.000263285,0.00004873502,0.0002097574,0.0009008551],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8692828,"threshold_uncertainty_score":0.9997061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04959611844506293,"score_gpt":0.3672500029767788,"score_spread":0.3176538845317159,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}