{"id":"W4396956974","doi":"10.4149/gpb_2024007","title":"Trivalent anions as probes of the CFTR channel pore","year":2024,"lang":"en","type":"article","venue":"General Physiology and Biophysics","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Channel (broadcasting); Computer science; Telecommunications","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004023872,0.00009557381,0.00008727981,0.00001770278,0.000082889,0.000007689854,0.00007266413,0.0001041654,0.000009104261],"category_scores_gemma":[0.000006371708,0.00006130556,0.00009244218,0.0001000707,0.0001396028,0.000003713959,0.00008089872,0.00006288474,0.000005088639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003300785,"about_ca_system_score_gemma":0.00003721753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006556728,"about_ca_topic_score_gemma":9.464878e-7,"domain_scores_codex":[0.9994889,0.00003741755,0.0001029082,0.0002104019,0.00005283101,0.000107546],"domain_scores_gemma":[0.9997469,0.00000466864,0.00003307241,0.0001509694,0.00003931913,0.00002512462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003777226,0.00003062672,0.00001946023,0.00003756713,0.00003903184,3.307003e-7,0.00004850765,0.0002226869,0.9915082,0.004882235,0.001922799,0.00125076],"study_design_scores_gemma":[0.0002497864,0.0003145299,0.005064184,0.0000248367,0.00003147035,0.00001903702,0.00004801229,0.002027311,0.9609705,0.009005994,0.02207972,0.000164616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975083,0.0005328347,0.000173541,0.0004451277,0.0008916357,0.0001167877,0.00002328261,0.00001258781,0.0002959257],"genre_scores_gemma":[0.9965568,0.0001880153,0.00003086776,0.0002561537,0.0009058436,0.00001091167,0.0001184855,0.000008990414,0.001923943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03053772,"threshold_uncertainty_score":0.2499968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00898161207232995,"score_gpt":0.235232272510284,"score_spread":0.2262506604379541,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}