{"id":"W4396991536","doi":"10.1681/asn.20213210s1415d","title":"The Utility of an Inherited Kidney Disease Clinic Employing a Broad Range of Genomic Testing Platforms: Experience of the Irish Kidney Gene Project","year":2021,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Irish; Kidney disease; Kidney; Disease; Medicine; Genetic testing; Gene; Biology; Bioinformatics; Genetics; Pathology; Internal medicine; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009483625,0.000454001,0.0003029604,0.0007762501,0.0007641613,0.001277882,0.0009235809,0.0004078475,0.001672058],"category_scores_gemma":[0.006930531,0.0002410921,0.0003496765,0.0007660369,0.001445798,0.0006490815,0.002553497,0.0006685864,0.0005224249],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001799809,"about_ca_system_score_gemma":0.004166306,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01685382,"about_ca_topic_score_gemma":0.02108014,"domain_scores_codex":[0.9954116,0.002236983,0.0002637891,0.0007269002,0.0008772328,0.000483466],"domain_scores_gemma":[0.9886235,0.003166432,0.001815901,0.0009618987,0.002379327,0.003052928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005017477,0.0002978592,0.8855726,0.0002044454,0.00008277113,0.003245758,0.002298969,0.0006010084,0.004618851,0.0004684516,0.005494839,0.09661283],"study_design_scores_gemma":[0.0001509912,0.002039355,0.9370782,0.0005459018,0.0001280759,0.01941225,0.005289679,0.002278393,0.005250096,0.0009851642,0.02670395,0.0001380002],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9790916,0.002300226,0.004364982,0.002897823,0.00009192267,0.0001721291,0.0009566385,0.0001506098,0.009974077],"genre_scores_gemma":[0.9852319,0.001411483,0.01022499,0.001382276,0.00006904682,0.00008156469,0.0005181409,0.00005652403,0.001023991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01685382,"threshold_uncertainty_score":0.05015481,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06576522930013562,"score_gpt":0.3534369009514024,"score_spread":0.2876716716512668,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}