{"id":"W4396992622","doi":"10.1681/asn.20213210s1729c","title":"Trial Design of FRONTIER: Ferric Citrate for the Prevention of Renal Failure in Adults with Advanced CKD","year":2021,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Dialysis and Renal Disease Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Medicine; Urology; Frontier; Ferric; Internal medicine; Intensive care medicine; Chemistry; Inorganic chemistry; Political science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01416988,0.00227572,0.003682268,0.0007572536,0.0007902657,0.001440116,0.001191432,0.003576569,0.01013085],"category_scores_gemma":[0.01571889,0.0007503004,0.002661786,0.0005533485,0.001735467,0.001574818,0.001257899,0.002614124,0.00111921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008241503,"about_ca_system_score_gemma":0.002725275,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006070782,"about_ca_topic_score_gemma":0.0007743805,"domain_scores_codex":[0.989805,0.008179741,0.0005222931,0.0006707796,0.0004076187,0.0004146542],"domain_scores_gemma":[0.9921848,0.003634725,0.001681208,0.0006689982,0.0007066828,0.001123624],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.9864611,0.0022043,0.0006204061,0.0009783404,0.001132467,0.00003816785,0.00004753347,0.0003365858,0.0004595283,0.0005584872,0.0007168482,0.006446126],"study_design_scores_gemma":[0.948284,0.04772529,0.0006216948,0.00008448154,0.0006789399,0.00002397715,0.00001510796,0.0005619896,0.0001542233,0.0006254565,0.001210978,0.00001385852],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.660792,0.009422841,0.01561337,0.006861225,0.005551985,0.2861703,0.004049242,0.0005633533,0.01097575],"genre_scores_gemma":[0.6165323,0.002334448,0.02196156,0.004359644,0.001740114,0.3454354,0.001182029,0.00004221403,0.006412397],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.01416988,"threshold_uncertainty_score":0.07493842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01524845886787482,"score_gpt":0.273995992362685,"score_spread":0.2587475334948102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}