{"id":"W4397008244","doi":"10.1590/1414-431x2024e12874","title":"Trichostatin A-modified vaccine provides superior protection against ovarian cancer formation and development","year":2024,"lang":"en","type":"article","venue":"Brazilian Journal of Medical and Biological Research","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"West China Hospital, Sichuan University; Sichuan University; China Postdoctoral Science Foundation","keywords":"Trichostatin A; Medicine; Ovarian cancer; Cancer; Biology; Internal medicine; Histone; Histone deacetylase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003842629,0.0001182634,0.0002520374,0.0002661251,0.0002892885,0.00008440675,0.0001853203,0.0003304877,0.000476172],"category_scores_gemma":[0.001199387,0.00006383242,0.00004367007,0.0002256086,0.0003022761,0.0001668424,0.00009541502,0.001003168,0.00001903762],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005032805,"about_ca_system_score_gemma":0.0003948952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002659438,"about_ca_topic_score_gemma":0.00001009641,"domain_scores_codex":[0.9980431,0.000740896,0.0004958106,0.0001762022,0.0002202134,0.0003238131],"domain_scores_gemma":[0.999097,0.0005381987,0.00006207783,0.00005660061,0.0001613776,0.00008477488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001685104,0.00007752537,0.000214175,0.0001014328,0.0001086322,0.0000634235,0.0007016284,1.472377e-7,0.1471805,0.0001356567,0.0007232203,0.8490086],"study_design_scores_gemma":[0.005710447,0.004001983,0.04518519,0.001952573,0.00002000471,0.002094562,0.001950284,0.0002317241,0.09085859,0.0005290819,0.8470981,0.000367487],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.933054,0.0565895,0.0007386921,0.009030732,0.0002583356,0.0002706728,0.000004187329,0.00001859441,0.00003532658],"genre_scores_gemma":[0.9825522,0.01671515,0.00009441659,0.0001347975,0.00008410606,0.0000324358,0.000007898136,0.000006476621,0.0003725413],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8486411,"threshold_uncertainty_score":0.5213749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0832606047798242,"score_gpt":0.3648869046960312,"score_spread":0.281626299916207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}