{"id":"W4397040375","doi":"10.1002/biof.2078","title":"Anticancer effect of minor phytocannabinoids in preclinical models of multiple myeloma","year":2024,"lang":"en","type":"article","venue":"BioFactors","topic":"Synthesis and bioactivity of alkaloids","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Decipher Biosciences (Canada); Altasciences (Canada)","funders":"Università degli Studi di Camerino","keywords":"In vivo; Bone resorption; Multiple myeloma; Cancer research; Osteoclast; Bone marrow; In vitro; Cancer; Medicine; Cancer cell; Osteoblast; Osteolysis; Pharmacology; Chemistry; Pathology; Internal medicine; Biology; Surgery; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002875186,0.0007045299,0.001086657,0.0009302602,0.0004094941,0.0003174017,0.0005115384,0.0005957036,0.001882407],"category_scores_gemma":[0.0001684154,0.0002917409,0.0007801801,0.000484287,0.0002915065,0.0004028336,0.0002781988,0.002357802,0.000308441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000507842,"about_ca_system_score_gemma":0.0005916037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001751937,"about_ca_topic_score_gemma":0.003736648,"domain_scores_codex":[0.999815,0.00002311,0.00002089162,0.00003207743,0.00006333972,0.00004559362],"domain_scores_gemma":[0.9998751,0.00001891856,0.00003105445,0.00001375786,0.00002365982,0.00003757349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003210869,0.003694419,0.0004458103,0.00106127,0.000148307,0.0002374267,0.0001094751,0.001195556,0.9719808,0.0004441006,0.001269033,0.01620294],"study_design_scores_gemma":[0.0007994532,0.02099582,0.006494523,0.0001233785,0.0004862831,0.000315468,0.0001222978,0.002382662,0.9499543,0.0004494619,0.01782958,0.00004666427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9563326,0.02692378,0.004450256,0.0009309306,0.0004289354,0.0005563088,0.003859667,0.0006060024,0.005911506],"genre_scores_gemma":[0.9643127,0.01865126,0.005219208,0.0005617379,0.0001105249,0.0007117827,0.002723789,0.00005158271,0.007657454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001882407,"threshold_uncertainty_score":0.00629729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02124128547546032,"score_gpt":0.2992390161817852,"score_spread":0.2779977307063248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}