{"id":"W4397040375","doi":"10.1002/biof.2078","title":"Anticancer effect of minor phytocannabinoids in preclinical models of multiple myeloma","year":2024,"lang":"en","type":"article","venue":"BioFactors","topic":"Synthesis and bioactivity of alkaloids","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Decipher Biosciences (Canada); Altasciences (Canada)","funders":"Università degli Studi di Camerino","keywords":"In vivo; Bone resorption; Multiple myeloma; Cancer research; Osteoclast; Bone marrow; In vitro; Cancer; Medicine; Cancer cell; Osteoblast; Osteolysis; Pharmacology; Chemistry; Pathology; Internal medicine; Biology; Surgery; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002612364,0.0001380637,0.0002713858,0.00007319219,0.00000917702,0.000007347075,0.0001335569,0.0001893113,0.00001552874],"category_scores_gemma":[0.0001170396,0.0001059787,0.0001840371,0.0001152858,0.0001394018,0.000006357434,0.000056595,0.00007263599,0.000001980479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001085374,"about_ca_system_score_gemma":0.00005968904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001310425,"about_ca_topic_score_gemma":0.00005975086,"domain_scores_codex":[0.9990754,0.00007050627,0.000268616,0.0002942671,0.0001277738,0.0001634602],"domain_scores_gemma":[0.9995463,0.0001000071,0.00005501916,0.0002305501,0.00002459559,0.00004349411],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002495314,0.00009462266,0.08990151,0.0002556652,0.00007669367,0.00000191934,0.00005375663,0.00002341918,0.8875419,0.00001984692,0.0002472951,0.02153382],"study_design_scores_gemma":[0.0003237095,0.000677824,0.0343275,0.0001101391,0.0000220189,0.000001215323,0.00001561495,0.0007136193,0.9621637,0.00002638871,0.00149361,0.000124689],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977339,0.001297558,0.0001304062,0.00004616509,0.0001940468,0.0001790028,0.00005615452,0.000009187938,0.0003536167],"genre_scores_gemma":[0.9994891,0.0001215498,0.0001345453,0.000009766812,0.00009296225,0.00001199887,0.00001682394,0.0000161683,0.0001070941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07462175,"threshold_uncertainty_score":0.4321687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02124128547546032,"score_gpt":0.2992390161817852,"score_spread":0.2779977307063248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}