{"id":"W4397040993","doi":"10.1681/asn.20233411s1603d","title":"Unbiased Proteomics Analysis Shows Distinct Graft Protein Expression in Donor-Specific Antibodies (DSA+) Kidney Transplant Recipients with Antibody-Mediated Rejection","year":2023,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Donor specific antibodies; Antibody; Protein expression; Kidney; Proteomics; Graft rejection; Medicine; Kidney transplantation; Immunology; Biology; Transplantation; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002197456,0.0001900005,0.0002428878,0.0007017523,0.000253747,0.0004064359,0.0001099347,0.0002174542,0.0009486601],"category_scores_gemma":[0.0002267684,0.000111638,0.0002393525,0.000541719,0.00019752,0.0001658574,0.000280242,0.0002470097,0.0002570415],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001280718,"about_ca_system_score_gemma":0.0001145007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002575839,"about_ca_topic_score_gemma":0.0003667172,"domain_scores_codex":[0.999806,0.00001615925,0.00001872896,0.00005469577,0.00006890378,0.00003560565],"domain_scores_gemma":[0.9998509,0.00002498237,0.00004765108,0.00001135811,0.00002727091,0.00003785173],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008570885,0.00004800754,0.05752209,0.00008182932,0.00007804047,0.0003658285,0.0001127062,0.00005595964,0.936167,0.00007215271,0.0001086754,0.004530711],"study_design_scores_gemma":[0.00001857259,0.0004416253,0.9018239,0.0000101605,0.00009699833,0.002475258,0.0002278699,0.0007835139,0.09267437,0.0001132342,0.001324064,0.00001035495],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980221,0.0005941911,0.0006687618,0.0000179312,0.000006669783,0.000006238702,0.0003555254,0.00001620403,0.0003124124],"genre_scores_gemma":[0.9971774,0.0005340797,0.001098494,0.00004557857,0.000009281846,0.00001729588,0.0007386543,0.000008562033,0.0003706267],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009486601,"threshold_uncertainty_score":0.00317359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01936291489078796,"score_gpt":0.2901918915966677,"score_spread":0.2708289767058797,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}