{"id":"W4397041272","doi":"10.1681/asn.20233411s1575a","title":"ABCC6 and CKD: The Phenotypic Expansion of Pseudoxanthoma Elasticum","year":2023,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Dermatological and Skeletal Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"","keywords":"Pseudoxanthoma elasticum; Medicine; Phenotype; Dermatology; Pathology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002612434,0.0005025237,0.0002602795,0.0008756741,0.0006835994,0.0002900499,0.0002993225,0.0006945917,0.003176343],"category_scores_gemma":[0.0009313831,0.0001358077,0.0002779636,0.0008486891,0.0004747715,0.0002887231,0.0006387761,0.0004831382,0.000234411],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001349253,"about_ca_system_score_gemma":0.0002306628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001072864,"about_ca_topic_score_gemma":0.001035296,"domain_scores_codex":[0.9997422,0.0000397836,0.00002628758,0.0000899498,0.0000635259,0.00003814108],"domain_scores_gemma":[0.9995634,0.000152199,0.0001441814,0.0000253652,0.00004773834,0.00006702786],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001264064,0.0002877509,0.6056708,0.0004004588,0.0002381311,0.2217552,0.001354503,0.0006246199,0.1271827,0.001690579,0.002571389,0.03695977],"study_design_scores_gemma":[0.00004386391,0.0001649281,0.5907778,0.00006735373,0.0001724262,0.3961498,0.000279684,0.0007605605,0.006456564,0.0008599369,0.004245,0.00002212473],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947034,0.001049746,0.001096678,0.0003531485,0.00002637059,0.00002275994,0.0003957469,0.00003790157,0.002314262],"genre_scores_gemma":[0.997552,0.0003875357,0.001071895,0.0001260151,0.00005072882,0.00001253548,0.0001860902,0.00001295611,0.0006001355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003176343,"threshold_uncertainty_score":0.0106259,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009226402705790001,"score_gpt":0.2461583690967475,"score_spread":0.2369319663909575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}