{"id":"W4397041777","doi":"10.1681/asn.20233411s11010d","title":"Deletion of IRE1α Exacerbates Diabetic Nephropathy in Mice","year":2023,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Birth, Development, and Health","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Diabetic nephropathy; Medicine; Nephropathy; Diabetes mellitus; Internal medicine; Endocrinology; Urology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004488685,0.001247703,0.0006509241,0.001108136,0.0003861315,0.0005618893,0.0004059687,0.0008146426,0.002483214],"category_scores_gemma":[0.0001802759,0.0006348505,0.0006254057,0.0003989249,0.000497396,0.0005091895,0.0004982268,0.001645193,0.0007016577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005335761,"about_ca_system_score_gemma":0.0003687243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004720868,"about_ca_topic_score_gemma":0.0009308822,"domain_scores_codex":[0.9995715,0.00005036044,0.00005465771,0.0001256362,0.00009204882,0.0001058399],"domain_scores_gemma":[0.999298,0.00003513573,0.0003446231,0.00004343051,0.00003793847,0.0002408989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007933347,0.0003463748,0.001026609,0.00009219319,0.00002681059,0.0002311238,0.00004202019,0.00008452211,0.9959369,0.0001289037,0.0001109125,0.001180271],"study_design_scores_gemma":[0.0005911952,0.005521411,0.05944054,0.0002239984,0.0003247909,0.004437535,0.0002636659,0.002491133,0.919093,0.0004465398,0.007115117,0.00005111299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933023,0.00134968,0.00207655,0.0002614229,0.00006976641,0.00007746697,0.0008585532,0.0002609839,0.001743394],"genre_scores_gemma":[0.9840583,0.002325721,0.005453284,0.0004291331,0.0000587882,0.0001810574,0.001453541,0.0001601925,0.005880037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002483214,"threshold_uncertainty_score":0.008307219,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02037183200506837,"score_gpt":0.292699686899266,"score_spread":0.2723278548941976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}