{"id":"W4397043226","doi":"10.1681/asn.20233411s1943a","title":"Complex Genetic in Autosomal Dominant Polycystic Kidney Disease (ADPKD)","year":2023,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; St. Joseph’s Healthcare Hamilton; University Health Network","funders":"","keywords":"Autosomal dominant polycystic kidney disease; Polycystic kidney; Polycystic kidney disease; Medicine; Kidney disease; Disease; Internal medicine; Biology; Genetics; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004083131,0.000612705,0.0002637347,0.001149514,0.0005743174,0.0006451341,0.0002497458,0.0004238389,0.003394007],"category_scores_gemma":[0.002231032,0.0001562201,0.0002462772,0.001050473,0.0005125864,0.0003620012,0.0007577177,0.0004008861,0.0003244529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003873434,"about_ca_system_score_gemma":0.0004073882,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002124069,"about_ca_topic_score_gemma":0.002621037,"domain_scores_codex":[0.9995695,0.00006725251,0.0000600159,0.0001075427,0.0001491484,0.00004649577],"domain_scores_gemma":[0.9991916,0.0002621423,0.0002905918,0.00005130972,0.00009200726,0.0001123205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007814643,0.000073166,0.9119684,0.0003530104,0.0002109422,0.02047042,0.0004330044,0.001277487,0.01772527,0.002008218,0.002038274,0.04266037],"study_design_scores_gemma":[0.00006438784,0.000204357,0.7397877,0.0001048493,0.0002056139,0.2362558,0.0002585193,0.002766879,0.007219763,0.003394448,0.009697565,0.00004016873],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882042,0.002425314,0.004025905,0.000293766,0.00001806397,0.00005943636,0.0009238483,0.00007496275,0.003974601],"genre_scores_gemma":[0.9960407,0.0005810196,0.002056203,0.000064446,0.00002461886,0.00001401171,0.0006818806,0.00001485928,0.0005223717],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003394007,"threshold_uncertainty_score":0.01135409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01224122177736967,"score_gpt":0.2631665264285135,"score_spread":0.2509253046511438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}