{"id":"W4398165220","doi":"10.1152/physiol.2024.39.s1.1400","title":"Chaos in the Colon: Unlocking the Puzzle of DRA (SLC26A3) Downregulation with IL-1α and p38 MAPK Amidst <i>Brachyspira</i> Turmoil","year":2024,"lang":"en","type":"article","venue":"Physiology","topic":"Veterinary medicine and infectious diseases","field":"Veterinary","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Downregulation and upregulation; CHAOS (operating system); Biology; Computer science; Genetics; Computer security","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001938116,0.0001467132,0.0002101808,0.00006923076,0.0001099244,0.00002243026,0.0001511605,0.00005693397,0.00006340204],"category_scores_gemma":[0.00002129953,0.00007532507,0.00004584062,0.0002546804,0.0002674464,0.0001248938,0.00006859475,0.0001837937,0.00001605925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002159467,"about_ca_system_score_gemma":0.00003056617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002028694,"about_ca_topic_score_gemma":0.00005006369,"domain_scores_codex":[0.9990212,0.0002111198,0.0001962759,0.0002538073,0.0001180509,0.0001995599],"domain_scores_gemma":[0.9993312,0.0002712669,0.00006237972,0.0002826063,0.0000278365,0.00002471042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00164791,0.0004090446,0.002699871,0.0008848578,0.0002125436,0.0003759401,0.007897604,0.0002350179,0.962926,0.009097982,0.00343771,0.01017554],"study_design_scores_gemma":[0.001911815,0.011496,0.9246829,0.0005973648,0.0002661035,0.001894537,0.004255318,0.005171048,0.002577881,0.006923289,0.03963,0.0005937277],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954191,0.0009535215,0.00001855824,0.0009329182,0.000149134,0.0002936352,0.00001714275,0.00005882455,0.002157185],"genre_scores_gemma":[0.9988911,0.00007863028,0.000008085437,0.0006159285,0.0002529148,0.00007565425,0.00002482075,0.00001695752,0.00003594258],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9603481,"threshold_uncertainty_score":0.3071667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03220586431197721,"score_gpt":0.3040598259904403,"score_spread":0.2718539616784631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}